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Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior.
Delbès AS, Quiñones M, Gobet C, Castel J, Denis RGP, Berthelet J, Weger BD, Challet E, Charpagne A, Metairon S, Piccand J, Kraus M, Rohde BH, Bial J, Wilson EM, Vedin LL, Minniti ME, Pedrelli M, Parini P, Gachon F, Luquet S. Delbès AS, et al. Among authors: gobet c. Sci Adv. 2023 May 19;9(20):eadf2982. doi: 10.1126/sciadv.adf2982. Epub 2023 May 17. Sci Adv. 2023. PMID: 37196091 Free PMC article.
Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.
Jouffe C, Weger BD, Martin E, Atger F, Weger M, Gobet C, Ramnath D, Charpagne A, Morin-Rivron D, Powell EE, Sweet MJ, Masoodi M, Uhlenhaut NH, Gachon F. Jouffe C, et al. Among authors: gobet c. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2200083119. doi: 10.1073/pnas.2200083119. Epub 2022 Mar 1. Proc Natl Acad Sci U S A. 2022. PMID: 35238641 Free PMC article.
Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle.
Perrin L, Loizides-Mangold U, Chanon S, Gobet C, Hulo N, Isenegger L, Weger BD, Migliavacca E, Charpagne A, Betts JA, Walhin JP, Templeman I, Stokes K, Thompson D, Tsintzas K, Robert M, Howald C, Riezman H, Feige JN, Karagounis LG, Johnston JD, Dermitzakis ET, Gachon F, Lefai E, Dibner C. Perrin L, et al. Among authors: gobet c. Elife. 2018 Apr 16;7:e34114. doi: 10.7554/eLife.34114. Elife. 2018. PMID: 29658882 Free PMC article.
23 results