Gobec S - Search Results

1

Antibacterial and β-Lactamase Inhibitory Activity of Monocyclic β-Lactams.

Decuyper L, Jukič M, Sosič I, Žula A, D'hooghe M, Gobec S. Decuyper L, et al. Among authors: gobec s. Med Res Rev. 2018 Mar;38(2):426-503. doi: 10.1002/med.21443. Epub 2017 Aug 16. Med Res Rev. 2018. PMID: 28815732 Review.

2

Discovery of novel benzene 1,3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach.

Perdih A, Kovac A, Wolber G, Blanot D, Gobec S, Solmajer T. Perdih A, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2009 May 15;19(10):2668-73. doi: 10.1016/j.bmcl.2009.03.141. Epub 2009 Apr 1. Bioorg Med Chem Lett. 2009. PMID: 19369074

3

Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase.

Zidar N, Tomasić T, Sink R, Rupnik V, Kovac A, Turk S, Patin D, Blanot D, Contreras Martel C, Dessen A, Müller Premru M, Zega A, Gobec S, Peterlin Masic L, Kikelj D. Zidar N, et al. Among authors: gobec s. J Med Chem. 2010 Sep 23;53(18):6584-94. doi: 10.1021/jm100285g. J Med Chem. 2010. PMID: 20804196

4

Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid.

Sosič I, Barreteau H, Simčič M, Sink R, Cesar J, Zega A, Grdadolnik SG, Contreras-Martel C, Dessen A, Amoroso A, Joris B, Blanot D, Gobec S. Sosič I, et al. Among authors: gobec s. Eur J Med Chem. 2011 Jul;46(7):2880-94. doi: 10.1016/j.ejmech.2011.04.011. Epub 2011 Apr 9. Eur J Med Chem. 2011. PMID: 21524830 Free article.

5

New noncovalent inhibitors of penicillin-binding proteins from penicillin-resistant bacteria.

Turk S, Verlaine O, Gerards T, Zivec M, Humljan J, Sosič I, Amoroso A, Zervosen A, Luxen A, Joris B, Gobec S. Turk S, et al. Among authors: gobec s. PLoS One. 2011 May 9;6(5):e19418. doi: 10.1371/journal.pone.0019418. PLoS One. 2011. PMID: 21573060 Free PMC article.

6

Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).

Tomasić T, Zidar N, Sink R, Kovac A, Blanot D, Contreras-Martel C, Dessen A, Müller-Premru M, Zega A, Gobec S, Kikelj D, Masic LP. Tomasić T, et al. Among authors: gobec s. J Med Chem. 2011 Jul 14;54(13):4600-10. doi: 10.1021/jm2002525. Epub 2011 Jun 3. J Med Chem. 2011. PMID: 21591605

7

Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds.

Mirković B, Renko M, Turk S, Sosič I, Jevnikar Z, Obermajer N, Turk D, Gobec S, Kos J. Mirković B, et al. Among authors: gobec s. ChemMedChem. 2011 Aug 1;6(8):1351-6. doi: 10.1002/cmdc.201100098. Epub 2011 May 20. ChemMedChem. 2011. PMID: 21598397 No abstract available.

8

Discovery and kinetic evaluation of 6-substituted 4-benzylthio-1,3,5-triazin-2(1H)-ones as inhibitors of cathepsin B.

Sosič I, Mirković B, Turk S, Štefaneb B, Kos J, Gobec S. Sosič I, et al. Among authors: gobec s. Eur J Med Chem. 2011 Sep;46(9):4648-56. doi: 10.1016/j.ejmech.2011.08.005. Epub 2011 Aug 9. Eur J Med Chem. 2011. PMID: 21849222

9

Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety.

Mirković B, Sosič I, Gobec S, Kos J. Mirković B, et al. Among authors: gobec s. PLoS One. 2011;6(11):e27197. doi: 10.1371/journal.pone.0027197. Epub 2011 Nov 4. PLoS One. 2011. PMID: 22073285 Free PMC article.

10

Expression of human aldo-keto reductase 1C2 in cell lines of peritoneal endometriosis: potential implications in metabolism of progesterone and dydrogesterone and inhibition by progestins.

Beranič N, Brožič P, Brus B, Sosič I, Gobec S, Lanišnik Rižner T. Beranič N, et al. Among authors: gobec s. J Steroid Biochem Mol Biol. 2012 May;130(1-2):16-25. doi: 10.1016/j.jsbmb.2011.12.011. Epub 2012 Jan 8. J Steroid Biochem Mol Biol. 2012. PMID: 22245609

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