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In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan.
Ribeiro R, Macedo JC, Costa M, Ustiyan V, Shindyapina AV, Tyshkovskiy A, Gomes RN, Castro JP, Kalin TV, Vasques-Nóvoa F, Nascimento DS, Dmitriev SE, Gladyshev VN, Kalinichenko VV, Logarinho E. Ribeiro R, et al. Among authors: gladyshev vn. Nat Aging. 2022 May;2(5):397-411. doi: 10.1038/s43587-022-00209-9. Epub 2022 May 5. Nat Aging. 2022. PMID: 37118067
DNA repair in species with extreme lifespan differences.
MacRae SL, Croken MM, Calder RB, Aliper A, Milholland B, White RR, Zhavoronkov A, Gladyshev VN, Seluanov A, Gorbunova V, Zhang ZD, Vijg J. MacRae SL, et al. Among authors: gladyshev vn. Aging (Albany NY). 2015 Dec;7(12):1171-84. doi: 10.18632/aging.100866. Aging (Albany NY). 2015. PMID: 26729707 Free PMC article.
Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan.
Patrick A, Seluanov M, Hwang C, Tam J, Khan T, Morgenstern A, Wiener L, Vazquez JM, Zafar H, Wen R, Muratkalyeva M, Doerig K, Zagorulya M, Cole L, Catalano S, Lobo Ladd AA, Coppi AA, Coşkun Y, Tian X, Ablaeva J, Nevo E, Gladyshev VN, Zhang ZD, Vijg J, Seluanov A, Gorbunova V. Patrick A, et al. Among authors: gladyshev vn. Aging (Albany NY). 2016 May;8(5):841-7. doi: 10.18632/aging.100958. Aging (Albany NY). 2016. PMID: 27163160 Free PMC article.
A whole lifespan mouse multi-tissue DNA methylation clock.
Meer MV, Podolskiy DI, Tyshkovskiy A, Gladyshev VN. Meer MV, et al. Among authors: gladyshev vn. Elife. 2018 Nov 14;7:e40675. doi: 10.7554/eLife.40675. Elife. 2018. PMID: 30427307 Free PMC article.
Reversibility of irreversible aging.
Galkin F, Zhang B, Dmitriev SE, Gladyshev VN. Galkin F, et al. Among authors: gladyshev vn. Ageing Res Rev. 2019 Jan;49:104-114. doi: 10.1016/j.arr.2018.11.008. Epub 2018 Dec 1. Ageing Res Rev. 2019. PMID: 30513346 Review.
450 results