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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers.
Kayed R, Head E, Sarsoza F, Saing T, Cotman CW, Necula M, Margol L, Wu J, Breydo L, Thompson JL, Rasool S, Gurlo T, Butler P, Glabe CG. Kayed R, et al. Among authors: glabe cg. Mol Neurodegener. 2007 Sep 26;2:18. doi: 10.1186/1750-1326-2-18. Mol Neurodegener. 2007. PMID: 17897471 Free PMC article.
Structural differences between amyloid beta oligomers.
Breydo L, Kurouski D, Rasool S, Milton S, Wu JW, Uversky VN, Lednev IK, Glabe CG. Breydo L, et al. Among authors: glabe cg. Biochem Biophys Res Commun. 2016 Sep 2;477(4):700-705. doi: 10.1016/j.bbrc.2016.06.122. Epub 2016 Jun 27. Biochem Biophys Res Commun. 2016. PMID: 27363332
157 results