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Assessing immunogenicity barriers of the HIV-1 envelope trimer.
Maliqi L, Friedrich N, Glögl M, Schmutz S, Schmidt D, Rusert P, Schanz M, Zaheri M, Pasin C, Niklaus C, Foulkes C, Reinberg T, Dreier B, Abela I, Peterhoff D, Hauser A, Kouyos RD, Günthard HF, van Gils MJ, Sanders RW, Wagner R, Plückthun A, Trkola A. Maliqi L, et al. Among authors: glogl m. NPJ Vaccines. 2023 Sep 30;8(1):148. doi: 10.1038/s41541-023-00746-3. NPJ Vaccines. 2023. PMID: 37777519 Free PMC article.
Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Glögl M, Friedrich N, Cerutti G, Lemmin T, Kwon YD, Gorman J, Maliqi L, Mittl PRE, Hesselman MC, Schmidt D, Weber J, Foulkes C, Dingens AS, Bylund T, Olia AS, Verardi R, Reinberg T, Baumann NS, Rusert P, Dreier B, Shapiro L, Kwong PD, Plückthun A, Trkola A. Glögl M, et al. Nat Struct Mol Biol. 2023 Sep;30(9):1323-1336. doi: 10.1038/s41594-023-01062-z. Epub 2023 Aug 21. Nat Struct Mol Biol. 2023. PMID: 37605043 Free PMC article.
Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Friedrich N, Stiegeler E, Glögl M, Lemmin T, Hansen S, Kadelka C, Wu Y, Ernst P, Maliqi L, Foulkes C, Morin M, Eroglu M, Liechti T, Ivan B, Reinberg T, Schaefer JV, Karakus U, Ursprung S, Mann A, Rusert P, Kouyos RD, Robinson JA, Günthard HF, Plückthun A, Trkola A. Friedrich N, et al. Among authors: glogl m. Nat Commun. 2021 Nov 18;12(1):6705. doi: 10.1038/s41467-021-27075-0. Nat Commun. 2021. PMID: 34795280 Free PMC article.