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Biliary atresia is associated with polygenic susceptibility in ciliogenesis and planar polarity effector genes.
Glessner JT, Ningappa MB, Ngo KA, Zahid M, So J, Higgs BW, Sleiman PMA, Narayanan T, Ranganathan S, March M, Prasadan K, Vaccaro C, Reyes-Mugica M, Velazquez J, Salgado CM, Ebrahimkhani MR, Schmitt L, Rajasundaram D, Paul M, Pellegrino R, Gittes GK, Li D, Wang X, Billings J, Squires R, Ashokkumar C, Sharif K, Kelly D, Dhawan A, Horslen S, Lo CW, Shin D, Subramaniam S, Hakonarson H, Sindhi R. Glessner JT, et al. Among authors: gittes gk. J Hepatol. 2023 Dec;79(6):1385-1395. doi: 10.1016/j.jhep.2023.07.039. Epub 2023 Aug 11. J Hepatol. 2023. PMID: 37572794 Free PMC article.
Acinar to β-like cell conversion through inhibition of focal adhesion kinase.
Dahiya S, Saleh M, Rodriguez UA, Rajasundaram D, R Arbujas J, Hajihassani A, Yang K, Sehrawat A, Kalsi R, Yoshida S, Prasadan K, Lickert H, Hu J, Piganelli JD, Gittes GK, Esni F. Dahiya S, et al. Among authors: gittes gk. Nat Commun. 2024 May 3;15(1):3740. doi: 10.1038/s41467-024-47972-4. Nat Commun. 2024. PMID: 38702347 Free PMC article.
Chemical pancreatectomy in non-human primates ablates the acini and ducts and enhances beta-cell function.
Kalsi RS, Kreger AM, Saleh M, Yoshida S, Sharma K, Fusco J, Saloman JL, Zhang T, Thomas M, Sehrawat A, Wang Y, Reif J, Mills J, Raad S, Zengin B, Gomez A, Singhi A, Tadros S, Slivka A, Esni F, Prasadan K, Gittes G. Kalsi RS, et al. Res Sq [Preprint]. 2023 Mar 8:rs.3.rs-2618133. doi: 10.21203/rs.3.rs-2618133/v1. Res Sq. 2023. PMID: 36945494 Free PMC article. Updated. Preprint.
A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.
Zou H, Poore B, Brown EE, Qian J, Xie B, Asimakidou E, Razskazovskiy V, Ayrapetian D, Sharma V, Xia S, Liu F, Chen A, Guan Y, Li Z, Wanggou S, Saulnier O, Ly M, Fellows-Mayle W, Xi G, Tomita T, Resnick AC, Mack SC, Raabe EH, Eberhart CG, Sun D, Stronach BE, Agnihotri S, Kohanbash G, Lu S, Herrup K, Rich JN, Gittes GK, Broniscer A, Hu Z, Li X, Pollack IF, Friedlander RM, Hainer SJ, Taylor MD, Hu B. Zou H, et al. Among authors: gittes gk. Nat Cell Biol. 2023 Mar;25(3):493-507. doi: 10.1038/s41556-023-01093-0. Epub 2023 Feb 27. Nat Cell Biol. 2023. PMID: 36849558 Free PMC article.
189 results