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Dissecting the genetic landscape of GPCR signaling through phenotypic profiling in C. elegans.
Pu L, Wang J, Lu Q, Nilsson L, Philbrook A, Pandey A, Zhao L, Schendel RV, Koh A, Peres TV, Hashi WH, Myint SL, Williams C, Gilthorpe JD, Wai SN, Brown A, Tijsterman M, Sengupta P, Henriksson J, Chen C. Pu L, et al. Among authors: gilthorpe jd. Nat Commun. 2023 Dec 18;14(1):8410. doi: 10.1038/s41467-023-44177-z. Nat Commun. 2023. PMID: 38110404 Free PMC article.
Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS.
Günther R, Pal A, Williams C, Zimyanin VL, Liehr M, von Neubeck C, Krause M, Parab MG, Petri S, Kalmbach N, Marklund SL, Sterneckert J, Munch Andersen P, Wegner F, Gilthorpe JD, Hermann A. Günther R, et al. Among authors: gilthorpe jd. Cells. 2022 Apr 6;11(7):1246. doi: 10.3390/cells11071246. Cells. 2022. PMID: 35406813 Free PMC article.
ApoE Isoforms Inhibit Amyloid Aggregation of Proinflammatory Protein S100A9.
Ghosh S, Tamilselvi S, Williams C, Jayaweera SW, Iashchishyn IA, Šulskis D, Gilthorpe JD, Olofsson A, Smirnovas V, Svedružić ŽM, Morozova-Roche LA. Ghosh S, et al. Among authors: gilthorpe jd. Int J Mol Sci. 2024 Feb 9;25(4):2114. doi: 10.3390/ijms25042114. Int J Mol Sci. 2024. PMID: 38396791 Free PMC article.
Publisher Correction: Altered perivascular fibroblast activity precedes ALS disease onset.
Månberg A, Skene N, Sanders F, Trusohamn M, Remnestål J, Szczepińska A, Aksoylu IS, Lönnerberg P, Ebarasi L, Wouters S, Lehmann M, Olofsson J, von Gohren Antequera I, Domaniku A, De Schaepdryver M, De Vocht J, Poesen K, Uhlén M, Anink J, Mijnsbergen C, Vergunst-Bosch H, Hübers A, Kläppe U, Rodriguez-Vieitez E, Gilthorpe JD, Hedlund E, Harris RA, Aronica E, Van Damme P, Ludolph A, Veldink J, Ingre C, Nilsson P, Lewandowski SA. Månberg A, et al. Among authors: gilthorpe jd. Nat Med. 2021 Jul;27(7):1308. doi: 10.1038/s41591-021-01414-6. Nat Med. 2021. PMID: 34079107 No abstract available.
Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models.
Devoy A, Price G, De Giorgio F, Bunton-Stasyshyn R, Thompson D, Gasco S, Allan A, Codner GF, Nair RR, Tibbit C, McLeod R, Ali Z, Noda J, Marrero-Gagliardi A, Brito-Armas JM, Williams C, Öztürk MM, Simon M, O'Neill E, Bryce-Smith S, Harrison J, Atkins G, Corrochano S, Stewart M, Gilthorpe JD, Teboul L, Acevedo-Arozena A, Fisher EMC, Cunningham TJ. Devoy A, et al. Among authors: gilthorpe jd. iScience. 2021 Nov 15;24(12):103463. doi: 10.1016/j.isci.2021.103463. eCollection 2021 Dec 17. iScience. 2021. PMID: 34988393 Free PMC article.
Altered perivascular fibroblast activity precedes ALS disease onset.
Månberg A, Skene N, Sanders F, Trusohamn M, Remnestål J, Szczepińska A, Aksoylu IS, Lönnerberg P, Ebarasi L, Wouters S, Lehmann M, Olofsson J, von Gohren Antequera I, Domaniku A, De Schaepdryver M, De Vocht J, Poesen K, Uhlén M, Anink J, Mijnsbergen C, Vergunst-Bosch H, Hübers A, Kläppe U, Rodriguez-Vieitez E, Gilthorpe JD, Hedlund E, Harris RA, Aronica E, Van Damme P, Ludolph A, Veldink J, Ingre C, Nilsson P, Lewandowski SA. Månberg A, et al. Among authors: gilthorpe jd. Nat Med. 2021 Apr;27(4):640-646. doi: 10.1038/s41591-021-01295-9. Epub 2021 Apr 15. Nat Med. 2021. PMID: 33859435 Free PMC article.
37 results