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Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases.
Yuan S, Wang L, Zhang H, Xu F, Zhou X, Yu L, Sun J, Chen J, Ying H, Xu X, Yu Y, Spiliopoulou A, Shen X, Wilson J, Gill D, Theodoratou E, Larsson SC, Li X. Yuan S, et al. Among authors: gill d. EBioMedicine. 2023 Mar;89:104488. doi: 10.1016/j.ebiom.2023.104488. Epub 2023 Feb 24. EBioMedicine. 2023. PMID: 36842216 Free PMC article.
Guidelines for performing Mendelian randomization investigations: update for summer 2023.
Burgess S, Davey Smith G, Davies NM, Dudbridge F, Gill D, Glymour MM, Hartwig FP, Kutalik Z, Holmes MV, Minelli C, Morrison JV, Pan W, Relton CL, Theodoratou E. Burgess S, et al. Among authors: gill d. Wellcome Open Res. 2023 Aug 4;4:186. doi: 10.12688/wellcomeopenres.15555.3. eCollection 2019. Wellcome Open Res. 2023. PMID: 32760811 Free PMC article.
Global assessment of C-reactive protein and health-related outcomes: an umbrella review of evidence from observational studies and Mendelian randomization studies.
Markozannes G, Koutsioumpa C, Cividini S, Monori G, Tsilidis KK, Kretsavos N, Theodoratou E, Gill D, Ioannidis JP, Tzoulaki I. Markozannes G, et al. Among authors: gill d. Eur J Epidemiol. 2021 Jan;36(1):11-36. doi: 10.1007/s10654-020-00681-w. Epub 2020 Sep 25. Eur J Epidemiol. 2021. PMID: 32978716 Free PMC article. Review.
Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.
Gill D, Cameron AC, Burgess S, Li X, Doherty DJ, Karhunen V, Abdul-Rahim AH, Taylor-Rowan M, Zuber V, Tsao PS, Klarin D; VA Million Veteran Program; Evangelou E, Elliott P, Damrauer SM, Quinn TJ, Dehghan A, Theodoratou E, Dawson J, Tzoulaki I. Gill D, et al. Hypertension. 2021 Feb;77(2):383-392. doi: 10.1161/HYPERTENSIONAHA.120.16547. Epub 2020 Dec 28. Hypertension. 2021. PMID: 33356394 Free PMC article.
ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study.
Gill D, Arvanitis M, Carter P, Hernández Cordero AI, Jo B, Karhunen V, Larsson SC, Li X, Lockhart SM, Mason A, Pashos E, Saha A, Tan VY, Zuber V, Bossé Y, Fahle S, Hao K, Jiang T, Joubert P, Lunt AC, Ouwehand WH, Roberts DJ, Timens W, van den Berge M, Watkins NA, Battle A, Butterworth AS, Danesh J, Di Angelantonio E, Engelhardt BE, Peters JE, Sin DD, Burgess S. Gill D, et al. R Soc Open Sci. 2020 Nov 18;7(11):200958. doi: 10.1098/rsos.200958. eCollection 2020 Nov. R Soc Open Sci. 2020. PMID: 33391794 Free PMC article.
1,858 results