Gilkes DM - Search Results

1

Hypoxia-inducible factor-dependent ADAM12 expression mediates breast cancer invasion and metastasis.

Wang R, Godet I, Yang Y, Salman S, Lu H, Lyu Y, Zuo Q, Wang Y, Zhu Y, Chen C, He J, Gilkes DM, Semenza GL. Wang R, et al. Among authors: gilkes dm. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2020490118. doi: 10.1073/pnas.2020490118. Proc Natl Acad Sci U S A. 2021. PMID: 33952697 Free PMC article.

2

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.

Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, Wirtz D, Semenza GL. Wong CC, et al. Among authors: gilkes dm. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16369-74. doi: 10.1073/pnas.1113483108. Epub 2011 Sep 12. Proc Natl Acad Sci U S A. 2011. PMID: 21911388 Free PMC article.

3

Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.

Hubbi ME, Gilkes DM, Baek JH, Semenza GL. Hubbi ME, et al. Among authors: gilkes dm. J Biol Chem. 2012 Feb 24;287(9):6139-49. doi: 10.1074/jbc.M111.278630. Epub 2012 Jan 4. J Biol Chem. 2012. PMID: 22219185 Free PMC article.

4

Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.

Wong CC, Zhang H, Gilkes DM, Chen J, Wei H, Chaturvedi P, Hubbi ME, Semenza GL. Wong CC, et al. Among authors: gilkes dm. J Mol Med (Berl). 2012 Jul;90(7):803-15. doi: 10.1007/s00109-011-0855-y. Epub 2012 Jan 10. J Mol Med (Berl). 2012. PMID: 22231744 Free PMC article.

5

Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis.

Chaturvedi P, Gilkes DM, Wong CC; Kshitiz; Luo W, Zhang H, Wei H, Takano N, Schito L, Levchenko A, Semenza GL. Chaturvedi P, et al. Among authors: gilkes dm. J Clin Invest. 2013 Jan;123(1):189-205. doi: 10.1172/JCI64993. Epub 2012 Dec 17. J Clin Invest. 2013. PMID: 23318994 Free PMC article.

6

Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis.

Gilkes DM, Bajpai S, Wong CC, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL. Gilkes DM, et al. Mol Cancer Res. 2013 May;11(5):456-66. doi: 10.1158/1541-7786.MCR-12-0629. Epub 2013 Feb 1. Mol Cancer Res. 2013. PMID: 23378577 Free PMC article. Retracted.

7

A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication.

Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL. Hubbi ME, et al. Among authors: gilkes dm. Sci Signal. 2013 Feb 12;6(262):ra10. doi: 10.1126/scisignal.2003417. Sci Signal. 2013. PMID: 23405012 Free PMC article.

8

Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts.

Gilkes DM, Bajpai S, Chaturvedi P, Wirtz D, Semenza GL. Gilkes DM, et al. J Biol Chem. 2013 Apr 12;288(15):10819-29. doi: 10.1074/jbc.M112.442939. Epub 2013 Feb 19. J Biol Chem. 2013. PMID: 23423382 Free PMC article. Retracted.

9

Collagen prolyl hydroxylases are essential for breast cancer metastasis.

Gilkes DM, Chaturvedi P, Bajpai S, Wong CC, Wei H, Pitcairn S, Hubbi ME, Wirtz D, Semenza GL. Gilkes DM, et al. Cancer Res. 2013 Jun 1;73(11):3285-96. doi: 10.1158/0008-5472.CAN-12-3963. Epub 2013 Mar 28. Cancer Res. 2013. PMID: 23539444 Free PMC article.

10

Sirtuin-7 inhibits the activity of hypoxia-inducible factors.

Hubbi ME, Hu H, Kshitiz, Gilkes DM, Semenza GL. Hubbi ME, et al. Among authors: gilkes dm. J Biol Chem. 2013 Jul 19;288(29):20768-20775. doi: 10.1074/jbc.M113.476903. Epub 2013 Jun 9. J Biol Chem. 2013. PMID: 23750001 Free PMC article.

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