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Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome.
Dinstag G, Shulman ED, Elis E, Ben-Zvi DS, Tirosh O, Maimon E, Meilijson I, Elalouf E, Temkin B, Vitkovsky P, Schiff E, Hoang DT, Sinha S, Nair NU, Lee JS, Schäffer AA, Ronai Z, Juric D, Apolo AB, Dahut WL, Lipkowitz S, Berger R, Kurzrock R, Papanicolau-Sengos A, Karzai F, Gilbert MR, Aldape K, Rajagopal PS, Beker T, Ruppin E, Aharonov R. Dinstag G, et al. Among authors: gilbert mr. Med. 2023 Jan 13;4(1):15-30.e8. doi: 10.1016/j.medj.2022.11.001. Epub 2022 Dec 12. Med. 2023. PMID: 36513065 Free PMC article.
Clinical impact of molecular profiling in rare brain tumors.
Pratt D, Penas-Prado M, Gilbert MR. Pratt D, et al. Among authors: gilbert mr. Curr Opin Neurol. 2023 Dec 1;36(6):579-586. doi: 10.1097/WCO.0000000000001211. Epub 2023 Oct 4. Curr Opin Neurol. 2023. PMID: 37973025 Review.
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, Merino-Galan L, Sulman E, Arowa S, Alvinez N, Jung M, Brown D, Tang K, Jackson S, Stoica S, Chittaboina P, Banasavadi-Siddegowda YK, Wirsching HG, Stella N, Shapiro L, Paddison P, Patel AP, Gilbert MR, Abdullaev Z, Aldape K, Pratt D, Holland EC, Cimino PJ. Nuechterlein N, et al. Among authors: gilbert mr. Genes Dev. 2024 Apr 17;38(5-6):273-288. doi: 10.1101/gad.351350.123. Genes Dev. 2024. PMID: 38589034
T cell exhaustion in malignant gliomas.
Watowich MB, Gilbert MR, Larion M. Watowich MB, et al. Among authors: gilbert mr. Trends Cancer. 2023 Apr;9(4):270-292. doi: 10.1016/j.trecan.2022.12.008. Epub 2023 Jan 19. Trends Cancer. 2023. PMID: 36681605 Free PMC article. Review.
Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency.
Kim O, Butler M, Sergi Z, Robey RW, Zhang M, Chari R, Pang Y, Yu G, Zhang W, Song H, Davis D, Hawley RG, Wen X, Wang H, Quezado M, Tran B, Merchant M, Ranjan A, Furnari FB, Khan J, Gilbert MR, Ryan Miller C, Gottesman MM, Pommier Y, Wu J. Kim O, et al. Among authors: gilbert mr. Neurooncol Adv. 2023 Aug 21;5(1):vdad102. doi: 10.1093/noajnl/vdad102. eCollection 2023 Jan-Dec. Neurooncol Adv. 2023. PMID: 37706203 Free PMC article.
Probabilistic model checking of cancer metabolism.
Friedenberg MD, Lita A, Gilbert MR, Larion M, Celiku O. Friedenberg MD, et al. Among authors: gilbert mr. Sci Rep. 2022 Nov 7;12(1):18870. doi: 10.1038/s41598-022-21846-5. Sci Rep. 2022. PMID: 36344581 Free PMC article.
Human endogenous retrovirus K contributes to a stem cell niche in glioblastoma.
Shah AH, Rivas SR, Doucet-O'Hare TT, Govindarajan V, DeMarino C, Wang T, Ampie L, Zhang Y, Banasavadi-Siddegowda YK, Walbridge S, Maric D, Garcia-Montojo M, Suter RK, Lee MH, Zaghloul KA, Steiner J, Elkahloun AG, Chandar J, Seetharam D, Desgraves J, Li W, Johnson K, Ivan ME, Komotar RJ, Gilbert MR, Heiss JD, Nath A. Shah AH, et al. Among authors: gilbert mr. J Clin Invest. 2023 Jul 3;133(13):e167929. doi: 10.1172/JCI167929. J Clin Invest. 2023. PMID: 37395282 Free PMC article.
rWTC-MBTA Vaccine Induces Potent Adaptive Immune Responses Against Glioblastomas via Dynamic Activation of Dendritic Cells.
Wang H, Medina R, Ye J, Zhang Y, Chakraborty S, Valenzuela A, Uher O, Hadrava Vanova K, Sun M, Sang X, Park DM, Zenka J, Gilbert MR, Pacak K, Zhuang Z. Wang H, et al. Among authors: gilbert mr. Adv Sci (Weinh). 2024 Apr;11(14):e2308280. doi: 10.1002/advs.202308280. Epub 2024 Jan 31. Adv Sci (Weinh). 2024. PMID: 38298111 Free PMC article.
463 results