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Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome.
Marcos-Ramiro B, Gil-Ordóñez A, Marín-Ramos NI, Ortega-Nogales FJ, Balabasquer M, Gonzalo P, Khiar-Fernández N, Rolas L, Barkaway A, Nourshargh S, Andrés V, Martín-Fontecha M, López-Rodríguez ML, Ortega-Gutiérrez S. Marcos-Ramiro B, et al. Among authors: gil ordonez a. ACS Cent Sci. 2021 Aug 25;7(8):1300-1310. doi: 10.1021/acscentsci.0c01698. Epub 2021 Jun 27. ACS Cent Sci. 2021. PMID: 34471675 Free PMC article.
A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia.
Marín-Ramos NI, Balabasquer M, Ortega-Nogales FJ, Torrecillas IR, Gil-Ordóñez A, Marcos-Ramiro B, Aguilar-Garrido P, Cushman I, Romero A, Medrano FJ, Gajate C, Mollinedo F, Philips MR, Campillo M, Gallardo M, Martín-Fontecha M, López-Rodríguez ML, Ortega-Gutiérrez S. Marín-Ramos NI, et al. Among authors: gil ordonez a. J Med Chem. 2019 Jul 11;62(13):6035-6046. doi: 10.1021/acs.jmedchem.9b00145. Epub 2019 Jun 19. J Med Chem. 2019. PMID: 31181882
Monoacylglycerol lipase (MAGL) as a promising therapeutic target.
Gil-Ordóñez A, Martín-Fontecha M, Ortega-Gutiérrez S, López-Rodríguez ML. Gil-Ordóñez A, et al. Biochem Pharmacol. 2018 Nov;157:18-32. doi: 10.1016/j.bcp.2018.07.036. Epub 2018 Jul 27. Biochem Pharmacol. 2018. PMID: 30059673 Review.