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Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine.
Wiley LK, Shortt JA, Roberts ER, Lowery J, Kudron E, Lin M, Mayer D, Wilson M, Brunetti TM, Chavan S, Phang TL, Pozdeyev N, Lesny J, Wicks SJ, Moore ET, Morgenstern JL, Roff AN, Shalowitz EL, Stewart A, Williams C, Edelmann MN, Hull M, Patton JT, Axell L, Ku L, Lee YM, Jirikowic J, Tanaka A, Todd E, White S, Peterson B, Hearst E, Zane R, Greene CS, Mathias R, Coors M, Taylor M, Ghosh D, Kahn MG, Brooks IM, Aquilante CL, Kao D, Rafaels N, Crooks KR, Hess S, Barnes KC, Gignoux CR. Wiley LK, et al. Among authors: gignoux cr. Am J Hum Genet. 2024 Jan 4;111(1):11-23. doi: 10.1016/j.ajhg.2023.12.001. Am J Hum Genet. 2024. PMID: 38181729 Free PMC article.
Host methylation predicts SARS-CoV-2 infection and clinical outcome.
Konigsberg IR, Barnes B, Campbell M, Davidson E, Zhen Y, Pallisard O, Boorgula MP, Cox C, Nandy D, Seal S, Crooks K, Sticca E, Harrison GF, Hopkinson A, Vest A, Arnold CG, Kahn MG, Kao DP, Peterson BR, Wicks SJ, Ghosh D, Horvath S, Zhou W, Mathias RA, Norman PJ, Porecha R, Yang IV, Gignoux CR, Monte AA, Taye A, Barnes KC. Konigsberg IR, et al. Among authors: gignoux cr. Commun Med (Lond). 2021 Oct 26;1(1):42. doi: 10.1038/s43856-021-00042-y. Commun Med (Lond). 2021. PMID: 36750622 Free article.
COVID-19 Mortality in the Colorado Center for Personalized Medicine Biobank.
Brice AN, Vanderlinden LA, Marker KM, Mayer D, Lin M, Rafaels N, Shortt JA, Romero A, Lowery JT, Gignoux CR, Johnson RK. Brice AN, et al. Among authors: gignoux cr. Int J Environ Res Public Health. 2023 Jan 29;20(3):2368. doi: 10.3390/ijerph20032368. Int J Environ Res Public Health. 2023. PMID: 36767733 Free PMC article.
Transcriptome-wide association study of the plasma proteome reveals cis and trans regulatory mechanisms underlying complex traits.
Wittich H, Ardlie K, Taylor KD, Durda P, Liu Y, Mikhaylova A, Gignoux CR, Cho MH, Rich SS, Rotter JI; NHLBI TOPMed Consortium; Manichaikul A, Im HK, Wheeler HE. Wittich H, et al. Among authors: gignoux cr. Am J Hum Genet. 2024 Mar 7;111(3):445-455. doi: 10.1016/j.ajhg.2024.01.006. Epub 2024 Feb 5. Am J Hum Genet. 2024. PMID: 38320554
Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations.
Araujo DS, Nguyen C, Hu X, Mikhaylova AV, Gignoux C, Ardlie K, Taylor KD, Durda P, Liu Y, Papanicolaou G, Cho MH, Rich SS, Rotter JI; NHLBI TOPMed Consortium; Im HK, Manichaikul A, Wheeler HE. Araujo DS, et al. bioRxiv [Preprint]. 2023 May 20:2023.02.09.527747. doi: 10.1101/2023.02.09.527747. bioRxiv. 2023. PMID: 36798214 Free PMC article. Updated. Preprint.
Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations.
Araujo DS, Nguyen C, Hu X, Mikhaylova AV, Gignoux C, Ardlie K, Taylor KD, Durda P, Liu Y, Papanicolaou G, Cho MH, Rich SS, Rotter JI; NHLBI TOPMed Consortium; Im HK, Manichaikul A, Wheeler HE. Araujo DS, et al. HGG Adv. 2023 Jul 1;4(4):100216. doi: 10.1016/j.xhgg.2023.100216. eCollection 2023 Oct 12. HGG Adv. 2023. PMID: 37869564 Free PMC article.
Poly-omic risk scores predict inflammatory bowel disease diagnosis.
Arehart CH, Sterrett JD, Garris RL, Quispe-Pilco RE, Gignoux CR, Evans LM, Stanislawski MA. Arehart CH, et al. Among authors: gignoux cr. mSystems. 2024 Jan 23;9(1):e0067723. doi: 10.1128/msystems.00677-23. Epub 2023 Dec 14. mSystems. 2024. PMID: 38095449 Free PMC article.
Characterizing substructure via mixture modeling in large-scale genetic summary statistics.
Stoneman HR, Price A, Scribner Trout N, Lamont R, Tifour S, Pozdeyev N; Colorado Center for Personalized Medicine; Crooks K, Lin M, Rafaels N, Gignoux CR, Marker KM, Hendricks AE. Stoneman HR, et al. Among authors: gignoux cr. bioRxiv [Preprint]. 2024 May 13:2024.01.29.577805. doi: 10.1101/2024.01.29.577805. bioRxiv. 2024. PMID: 38766180 Free PMC article. Preprint.
124 results