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Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1.
Giastas P, Mpakali A, Papakyriakou A, Lelis A, Kokkala P, Neu M, Rowland P, Liddle J, Georgiadis D, Stratikos E. Giastas P, et al. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26709-26716. doi: 10.1073/pnas.1912070116. Epub 2019 Dec 16. Proc Natl Acad Sci U S A. 2019. PMID: 31843903 Free PMC article.
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing.
Evnouchidou I, Birtley J, Seregin S, Papakyriakou A, Zervoudi E, Samiotaki M, Panayotou G, Giastas P, Petrakis O, Georgiadis D, Amalfitano A, Saridakis E, Mavridis IM, Stratikos E. Evnouchidou I, et al. Among authors: giastas p. J Immunol. 2012 Sep 1;189(5):2383-92. doi: 10.4049/jimmunol.1200918. Epub 2012 Jul 25. J Immunol. 2012. PMID: 22837489 Free PMC article.
Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency.
Mpakali A, Giastas P, Deprez-Poulain R, Papakyriakou A, Koumantou D, Gealageas R, Tsoukalidou S, Vourloumis D, Mavridis IM, Stratikos E, Saridakis E. Mpakali A, et al. Among authors: giastas p. ACS Med Chem Lett. 2017 Feb 21;8(3):333-337. doi: 10.1021/acsmedchemlett.6b00505. eCollection 2017 Mar 9. ACS Med Chem Lett. 2017. PMID: 28337326 Free PMC article.
Molecular recognition of N-acetyltryptophan enantiomers by β-cyclodextrin.
Chatziefthimiou SD, Inclán M, Giastas P, Papakyriakou A, Yannakopoulou K, Mavridis IM. Chatziefthimiou SD, et al. Among authors: giastas p. Beilstein J Org Chem. 2017 Aug 9;13:1572-1582. doi: 10.3762/bjoc.13.157. eCollection 2017. Beilstein J Org Chem. 2017. PMID: 28904606 Free PMC article.
Crystal Structure of the Monomeric Extracellular Domain of α9 Nicotinic Receptor Subunit in Complex With α-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to α9α10 Nicotinic Receptors.
Zouridakis M, Papakyriakou A, Ivanov IA, Kasheverov IE, Tsetlin V, Tzartos S, Giastas P. Zouridakis M, et al. Among authors: giastas p. Front Pharmacol. 2019 May 1;10:474. doi: 10.3389/fphar.2019.00474. eCollection 2019. Front Pharmacol. 2019. PMID: 31118896 Free PMC article.
35 results