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A highly efficient transgene knock-in technology in clinically relevant cell types.
Allen AG, Khan SQ, Margulies CM, Viswanathan R, Lele S, Blaha L, Scott SN, Izzo KM, Gerew A, Pattali R, Cochran NR, Holland CS, Zhao AH, Sherman SE, Jaskolka MC, Wu M, Wilson AC, Sun X, Ciulla DM, Zhang D, Nelson JD, Zhang P, Mazzucato P, Huang Y, Giannoukos G, Marco E, Nehil M, Follit JA, Chang KH, Shearman MS, Wilson CJ, Zuris JA. Allen AG, et al. Among authors: giannoukos g. Nat Biotechnol. 2024 Mar;42(3):458-469. doi: 10.1038/s41587-023-01779-8. Epub 2023 May 1. Nat Biotechnol. 2024. PMID: 37127662
Methylation-Sensitive Restriction Enzyme Quantitative Polymerase Chain Reaction Enables Rapid, Accurate, and Precise Detection of Methylation Status of the Regulatory T Cell (Treg)-Specific Demethylation Region in Primary Human Tregs.
Perry N, Wasko K, Cheng J, Tabbaa D, Marco E, Giannoukos G, Albright CF, Borges CM. Perry N, et al. Among authors: giannoukos g. J Immunol. 2021 Jan 15;206(2):446-451. doi: 10.4049/jimmunol.1901275. Epub 2020 Dec 4. J Immunol. 2021. PMID: 33277386
Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10.
Maeder ML, Stefanidakis M, Wilson CJ, Baral R, Barrera LA, Bounoutas GS, Bumcrot D, Chao H, Ciulla DM, DaSilva JA, Dass A, Dhanapal V, Fennell TJ, Friedland AE, Giannoukos G, Gloskowski SW, Glucksmann A, Gotta GM, Jayaram H, Haskett SJ, Hopkins B, Horng JE, Joshi S, Marco E, Mepani R, Reyon D, Ta T, Tabbaa DG, Samuelsson SJ, Shen S, Skor MN, Stetkiewicz P, Wang T, Yudkoff C, Myer VE, Albright CF, Jiang H. Maeder ML, et al. Among authors: giannoukos g. Nat Med. 2019 Feb;25(2):229-233. doi: 10.1038/s41591-018-0327-9. Epub 2019 Jan 21. Nat Med. 2019. PMID: 30664785
UDiTaS™, a genome editing detection method for indels and genome rearrangements.
Giannoukos G, Ciulla DM, Marco E, Abdulkerim HS, Barrera LA, Bothmer A, Dhanapal V, Gloskowski SW, Jayaram H, Maeder ML, Skor MN, Wang T, Myer VE, Wilson CJ. Giannoukos G, et al. BMC Genomics. 2018 Mar 21;19(1):212. doi: 10.1186/s12864-018-4561-9. BMC Genomics. 2018. PMID: 29562890 Free PMC article.
Simultaneous generation of many RNA-seq libraries in a single reaction.
Shishkin AA, Giannoukos G, Kucukural A, Ciulla D, Busby M, Surka C, Chen J, Bhattacharyya RP, Rudy RF, Patel MM, Novod N, Hung DT, Gnirke A, Garber M, Guttman M, Livny J. Shishkin AA, et al. Among authors: giannoukos g. Nat Methods. 2015 Apr;12(4):323-5. doi: 10.1038/nmeth.3313. Epub 2015 Mar 2. Nat Methods. 2015. PMID: 25730492 Free PMC article.
Functional optimization of gene clusters by combinatorial design and assembly.
Smanski MJ, Bhatia S, Zhao D, Park Y, B A Woodruff L, Giannoukos G, Ciulla D, Busby M, Calderon J, Nicol R, Gordon DB, Densmore D, Voigt CA. Smanski MJ, et al. Among authors: giannoukos g. Nat Biotechnol. 2014 Dec;32(12):1241-9. doi: 10.1038/nbt.3063. Epub 2014 Nov 24. Nat Biotechnol. 2014. PMID: 25419741
Relating the metatranscriptome and metagenome of the human gut.
Franzosa EA, Morgan XC, Segata N, Waldron L, Reyes J, Earl AM, Giannoukos G, Boylan MR, Ciulla D, Gevers D, Izard J, Garrett WS, Chan AT, Huttenhower C. Franzosa EA, et al. Among authors: giannoukos g. Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2329-38. doi: 10.1073/pnas.1319284111. Epub 2014 May 19. Proc Natl Acad Sci U S A. 2014. PMID: 24843156 Free PMC article.
Evaluation of 16S rDNA-based community profiling for human microbiome research.
Jumpstart Consortium Human Microbiome Project Data Generation Working Group. Jumpstart Consortium Human Microbiome Project Data Generation Working Group. PLoS One. 2012;7(6):e39315. doi: 10.1371/journal.pone.0039315. Epub 2012 Jun 13. PLoS One. 2012. PMID: 22720093 Free PMC article.
31 results