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Notch-dependent and -independent functions of transcription factor RBPJ.
Friedrich T, Ferrante F, Pioger L, Nist A, Stiewe T, Andrau JC, Bartkuhn M, Giaimo BD, Borggrefe T. Friedrich T, et al. Among authors: giaimo bd. Nucleic Acids Res. 2022 Aug 12;50(14):7925-7937. doi: 10.1093/nar/gkac601. Nucleic Acids Res. 2022. PMID: 35848919 Free PMC article.
A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes.
Oswald F, Rodriguez P, Giaimo BD, Antonello ZA, Mira L, Mittler G, Thiel VN, Collins KJ, Tabaja N, Cizelsky W, Rothe M, Kühl SJ, Kühl M, Ferrante F, Hein K, Kovall RA, Dominguez M, Borggrefe T. Oswald F, et al. Among authors: giaimo bd. Nucleic Acids Res. 2016 Jun 2;44(10):4703-20. doi: 10.1093/nar/gkw105. Epub 2016 Feb 23. Nucleic Acids Res. 2016. PMID: 26912830 Free PMC article.
Dynamic chromatin regulation at Notch target genes.
Giaimo BD, Oswald F, Borggrefe T. Giaimo BD, et al. Transcription. 2017 Jan;8(1):61-66. doi: 10.1080/21541264.2016.1265702. Epub 2016 Dec 27. Transcription. 2017. PMID: 28027012 Free PMC article.
HDAC3 functions as a positive regulator in Notch signal transduction.
Ferrante F, Giaimo BD, Bartkuhn M, Zimmermann T, Close V, Mertens D, Nist A, Stiewe T, Meier-Soelch J, Kracht M, Just S, Klöble P, Oswald F, Borggrefe T. Ferrante F, et al. Among authors: giaimo bd. Nucleic Acids Res. 2020 Apr 17;48(7):3496-3512. doi: 10.1093/nar/gkaa088. Nucleic Acids Res. 2020. PMID: 32107550 Free PMC article.
RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1.
Xu T, Park SS, Giaimo BD, Hall D, Ferrante F, Ho DM, Hori K, Anhezini L, Ertl I, Bartkuhn M, Zhang H, Milon E, Ha K, Conlon KP, Kuick R, Govindarajoo B, Zhang Y, Sun Y, Dou Y, Basrur V, Elenitoba-Johnson KS, Nesvizhskii AI, Ceron J, Lee CY, Borggrefe T, Kovall RA, Rual JF. Xu T, et al. Among authors: giaimo bd. EMBO J. 2017 Nov 2;36(21):3232-3249. doi: 10.15252/embj.201796525. Epub 2017 Oct 13. EMBO J. 2017. PMID: 29030483 Free PMC article.
Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes.
Diéguez-Hurtado R, Kato K, Giaimo BD, Nieminen-Kelhä M, Arf H, Ferrante F, Bartkuhn M, Zimmermann T, Bixel MG, Eilken HM, Adams S, Borggrefe T, Vajkoczy P, Adams RH. Diéguez-Hurtado R, et al. Among authors: giaimo bd. Nat Commun. 2019 Jun 27;10(1):2817. doi: 10.1038/s41467-019-10643-w. Nat Commun. 2019. PMID: 31249304 Free PMC article.
27 results