Ghosez L - Search Results

1

Discovery of a subnanomolar and selective spirocyclic agonist of the glucocorticoid receptor.

Badarau E, Robert F, Massip S, Jakob F, Lucas S, Friebe D, Hennen S, Frormann S, Ghosez L. Badarau E, et al. Among authors: ghosez l. Eur J Med Chem. 2019 Jan 1;161:354-363. doi: 10.1016/j.ejmech.2018.10.032. Epub 2018 Oct 15. Eur J Med Chem. 2019. PMID: 30384041

2

Productive Syntheses of Privileged Scaffolds Inspired by the Recognition of a Diels-Alder Pattern Common to Three Classes of Natural Products.

Badarau E, Reddy KHV, Loudet A, Simon C, Trembleau L, Claerhout S, Pair E, Massip S, Breton P, Lesur B, Goldstein S, Fourquez JM, Henlin JM, Ghosez L. Badarau E, et al. Among authors: ghosez l. Chemistry. 2020 Dec 1;26(67):15477-15481. doi: 10.1002/chem.202002372. Epub 2020 Sep 17. Chemistry. 2020. PMID: 32428343

3

Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases?

Dessolin J, Schuler M, Quinart A, De Giorgi F, Ghosez L, Ichas F. Dessolin J, et al. Among authors: ghosez l. Eur J Pharmacol. 2002 Jul 5;447(2-3):155-61. doi: 10.1016/s0014-2999(02)01839-3. Eur J Pharmacol. 2002. PMID: 12151007

4

Mechanisms and Conformational Control of (4 + 2) and (2 + 2) Cycloadditions of Dienes to Keteniminium Cations.

Ramirez M, Li W, Lam YH, Ghosez L, Houk KN. Ramirez M, et al. Among authors: ghosez l. J Org Chem. 2020 Feb 21;85(4):2597-2606. doi: 10.1021/acs.joc.9b03340. Epub 2020 Jan 23. J Org Chem. 2020. PMID: 31917921

5

Coupling products of amino acids to penicillin V and cephalothin: synthesis and susceptibility to carboxypeptidases and lysosomal enzymes.

Bounkhala Z, Renard C, Baurain R, Marchand-Brynaert J, Ghosez L, Tulkens PM. Bounkhala Z, et al. Among authors: ghosez l. J Med Chem. 1988 May;31(5):976-83. doi: 10.1021/jm00400a015. J Med Chem. 1988. PMID: 3129562

6

Multicomponent reactions for the synthesis of complex piperidine scaffolds.

Zhu W, Mena M, Jnoff E, Sun N, Pasau P, Ghosez L. Zhu W, et al. Among authors: ghosez l. Angew Chem Int Ed Engl. 2009;48(32):5880-3. doi: 10.1002/anie.200806065. Angew Chem Int Ed Engl. 2009. PMID: 19308937 No abstract available.

7

Enantioselective vicinal bis-acylation of olefins.

Ghosez L, Mahuteau-Betzer F, Genicot C, Vallribera A, Cordier JF. Ghosez L, et al. Chemistry. 2002 Aug 2;8(15):3411-22. doi: 10.1002/1521-3765(20020802)8:15<3411::AID-CHEM3411>3.0.CO;2-A. Chemistry. 2002. PMID: 12203321

8

Computational Exploration of Anomalous Regioselectivities in Cycloadditions of Ketenes to Oxazolines.

Zhu L, Maskeri MA, Ramirez M, Le Bideau F, Ghosez L, Houk KN. Zhu L, et al. Among authors: ghosez l. J Org Chem. 2022 Mar 4;87(5):3613-3622. doi: 10.1021/acs.joc.2c00001. Epub 2022 Jan 25. J Org Chem. 2022. PMID: 35076243

9

A Convergent Strategy for the Asymmetric Synthesis of Enantiomerically Pure Bicyclic Compounds by Using a Silicon-Directed Cycloaddition Reaction: The Synthesis of Enantiomerically Pure Bicyclo.

Adam JM, Ghosez L, Houk KN. Adam JM, et al. Among authors: ghosez l. Angew Chem Int Ed Engl. 1999 Sep;38(18):2728-2730. doi: 10.1002/(sici)1521-3773(19990917)38:18<2728::aid-anie2728>3.0.co;2-0. Angew Chem Int Ed Engl. 1999. PMID: 10508362

10

Design, synthesis and evaluation of D,D-peptidase and beta-lactamase inhibitors: azapeptides, oxapeptides and related heterocycles.

Marchand-Brynaert J, Mougenot P, Combret Y, Belotti D, Guillot N, Ghosez L. Marchand-Brynaert J, et al. Among authors: ghosez l. Farmaco. 1995 Jun;50(6):455-69. Farmaco. 1995. PMID: 7669184 Review.

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