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Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions.
Mol Cell. 2020 Dec 17;80(6):1092-1103.e4. doi: 10.1016/j.molcel.2020.11.025. Epub 2020 Nov 20.
Mol Cell. 2020.
PMID: 33248025
Free PMC article.
Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site.
Rosen LE, Klebba JE, Asfaha JB, Ghent CM, Campbell MG, Cheng Y, Morgan DO.
Rosen LE, et al. Among authors: ghent cm.
Nat Commun. 2019 Nov 15;10(1):5189. doi: 10.1038/s41467-019-13209-y.
Nat Commun. 2019.
PMID: 31729382
Free PMC article.
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Phosphorylation modulates liquid-liquid phase separation of the SARS-CoV-2 N protein.
Carlson CR, Asfaha JB, Ghent CM, Howard CJ, Hartooni N, Morgan DO.
Carlson CR, et al. Among authors: ghent cm.
bioRxiv [Preprint]. 2020 Jun 29:2020.06.28.176248. doi: 10.1101/2020.06.28.176248.
bioRxiv. 2020.
PMID: 32637943
Free PMC article.
Updated.
Preprint.
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Structural basis of human separase regulation by securin and CDK1-cyclin B1.
Yu J, Raia P, Ghent CM, Raisch T, Sadian Y, Cavadini S, Sabale PM, Barford D, Raunser S, Morgan DO, Boland A.
Yu J, et al. Among authors: ghent cm.
Nature. 2021 Aug;596(7870):138-142. doi: 10.1038/s41586-021-03764-0. Epub 2021 Jul 21.
Nature. 2021.
PMID: 34290405
Free PMC article.
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