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Anti-cancer activity of two novel heterocyclic compounds through modulation of VEGFR and miR-122 in mice bearing Ehrlich ascites carcinoma.
Eur J Pharmacol. 2021 Feb 5;892:173747. doi: 10.1016/j.ejphar.2020.173747. Epub 2020 Nov 21.
Eur J Pharmacol. 2021.
PMID: 33232730
Synthesis, molecular modelling, and preliminary anticonvulsant activity evaluation of novel naphthalen-2-yl acetate and 1,6-dithia-4,9-diazaspiro [4.4] nonane-3,8-dione derivatives.
Ghareb N, Abdel Daim MM, El-Sayed NM, Elgawish MS.
Ghareb N, et al.
Bioorg Chem. 2017 Apr;71:110-119. doi: 10.1016/j.bioorg.2017.01.018. Epub 2017 Jan 25.
Bioorg Chem. 2017.
PMID: 28162233
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Toward a treatment of diabesity: Rational design, synthesis and biological evaluation of benzene-sulfonamide derivatives as a new class of PTP-1B inhibitors.
Ghareb N, El-Sayed NM, Abdelhameed R, Yamada K, Elgawish MS.
Ghareb N, et al.
Bioorg Chem. 2019 May;86:322-338. doi: 10.1016/j.bioorg.2019.01.052. Epub 2019 Jan 31.
Bioorg Chem. 2019.
PMID: 30743173
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2-Phenylquinazolin-4(3H)-one scaffold as newly designed, synthesized VEGFR-2 allosteric inhibitors with potent cytotoxicity through apoptosis.
Elrayess R, Elgawish MS, Nafie MS, Ghareb N, Yassen ASA.
Elrayess R, et al. Among authors: ghareb n.
Arch Pharm (Weinheim). 2023 Jun;356(6):e2200654. doi: 10.1002/ardp.202200654. Epub 2023 Mar 31.
Arch Pharm (Weinheim). 2023.
PMID: 37002183
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Novel pyrazoles and pyrazolo[1,2-a]pyridazines as selective COX-2 inhibitors; Ultrasound-assisted synthesis, biological evaluation, and DFT calculations.
Ghareb N, Elshihawy HA, Abdel-Daim MM, Helal MA.
Ghareb N, et al.
Bioorg Med Chem Lett. 2017 Jun 1;27(11):2377-2383. doi: 10.1016/j.bmcl.2017.04.020. Epub 2017 Apr 8.
Bioorg Med Chem Lett. 2017.
PMID: 28427813
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Synthesis and biological activity of functionalized indole-2-carboxylates, triazino- and pyridazino-indoles.
El-Gendy AA, Said MM, Ghareb N, Mostafa YM, El-Ashry el SH.
El-Gendy AA, et al. Among authors: ghareb n.
Arch Pharm (Weinheim). 2008 May;341(5):294-300. doi: 10.1002/ardp.200700161.
Arch Pharm (Weinheim). 2008.
PMID: 18404776
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