Ghanem G - Search Results

1

Downregulation of the FTO m⁶A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors.

Jeschke J, Collignon E, Al Wardi C, Krayem M, Bizet M, Jia Y, Garaud S, Wimana Z, Calonne E, Hassabi B, Morandini R, Deplus R, Putmans P, Dube G, Singh NK, Koch A, Shostak K, Rizzotto L, Ross RL, Desmedt C, Bareche Y, Rothé F, Lehmann-Che J, Duterque-Coquillaud M, Leroy X, Menschaert G, Teixeira L, Guo M, Limbach PA, Close P, Chariot A, Leucci E, Ghanem G, Yuan BF, Willard-Gallo K, Sotiriou C, Marine JC, Fuks F. Jeschke J, et al. Among authors: ghanem g. Nat Cancer. 2021 Jun;2(6):611-628. doi: 10.1038/s43018-021-00223-7. Epub 2021 Jun 23. Nat Cancer. 2021. PMID: 35121941 Free PMC article.

2

Corrigendum to 'p53 Reactivation by PRIMA-1Met (APR-246) sensitises V600E/KBRAF melanoma to vemurafenib'[Eur J of Cancer 55 (2016) 98-110].

Krayem M, Journe F, Wiedig M, Morandini R, Najem A, Salès F, van Kempen LC, Sibille C, Awada A, Marine JC, Ghanem G. Krayem M, et al. Among authors: ghanem g. Eur J Cancer. 2022 Nov;175:336-338. doi: 10.1016/j.ejca.2022.09.002. Epub 2022 Sep 24. Eur J Cancer. 2022. PMID: 36167622 No abstract available.

3

Recent advances in radiosensitivity determinants in melanoma.

Krayem M, Ghanem GE, Van Gestel D. Krayem M, et al. Curr Opin Oncol. 2022 Mar 1;34(2):131-138. doi: 10.1097/CCO.0000000000000818. Curr Opin Oncol. 2022. PMID: 35013044 Review.

4

Prominent role of cyclic adenosine monophosphate signalling pathway in the sensitivity of (WT)BRAF/(WT)NRAS melanoma cells to vemurafenib.

Krayem M, Journe F, Wiedig M, Morandini R, Sales F, Awada A, Ghanem G. Krayem M, et al. Among authors: ghanem g. Eur J Cancer. 2014 May;50(7):1310-20. doi: 10.1016/j.ejca.2014.01.021. Epub 2014 Feb 19. Eur J Cancer. 2014. PMID: 24559688

5

p53 Reactivation by PRIMA-1(Met) (APR-246) sensitises (V600E/K)BRAF melanoma to vemurafenib.

Krayem M, Journe F, Wiedig M, Morandini R, Najem A, Salès F, van Kempen LC, Sibille C, Awada A, Marine JC, Ghanem G. Krayem M, et al. Among authors: ghanem g. Eur J Cancer. 2016 Mar;55:98-110. doi: 10.1016/j.ejca.2015.12.002. Epub 2016 Jan 17. Eur J Cancer. 2016. PMID: 26790143

6

Acquired resistance to BRAFi reverses senescence-like phenotype in mutant BRAF melanoma.

Krayem M, Najem A, Journe F, Morandini R, Sales F, Awada A, Ghanem GE. Krayem M, et al. Oncotarget. 2018 Aug 7;9(61):31888-31903. doi: 10.18632/oncotarget.25879. eCollection 2018 Aug 7. Oncotarget. 2018. PMID: 30159130 Free PMC article.

7

Tyrosine-Dependent Phenotype Switching Occurs Early in Many Primary Melanoma Cultures Limiting Their Translational Value.

Najem A, Wouters J, Krayem M, Rambow F, Sabbah M, Sales F, Awada A, Aerts S, Journe F, Marine JC, Ghanem GE. Najem A, et al. Front Oncol. 2021 Nov 11;11:780654. doi: 10.3389/fonc.2021.780654. eCollection 2021. Front Oncol. 2021. PMID: 34869032 Free PMC article.

8

RTK Inhibitors in Melanoma: From Bench to Bedside.

Sabbah M, Najem A, Krayem M, Awada A, Journe F, Ghanem GE. Sabbah M, et al. Cancers (Basel). 2021 Apr 2;13(7):1685. doi: 10.3390/cancers13071685. Cancers (Basel). 2021. PMID: 33918490 Free PMC article. Review.

9

Understanding Molecular Mechanisms of Phenotype Switching and Crosstalk with TME to Reveal New Vulnerabilities of Melanoma.

Najem A, Soumoy L, Sabbah M, Krayem M, Awada A, Journe F, Ghanem GE. Najem A, et al. Cells. 2022 Mar 29;11(7):1157. doi: 10.3390/cells11071157. Cells. 2022. PMID: 35406721 Free PMC article. Review.

10

A non-coding function of TYRP1 mRNA promotes melanoma growth.

Gilot D, Migault M, Bachelot L, Journé F, Rogiers A, Donnou-Fournet E, Mogha A, Mouchet N, Pinel-Marie ML, Mari B, Montier T, Corre S, Gautron A, Rambow F, El Hajj P, Ben Jouira R, Tartare-Deckert S, Marine JC, Felden B, Ghanem G, Galibert MD. Gilot D, et al. Among authors: ghanem g. Nat Cell Biol. 2017 Nov;19(11):1348-1357. doi: 10.1038/ncb3623. Epub 2017 Oct 9. Nat Cell Biol. 2017. PMID: 28991221 Free article.

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