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Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease.
Venegas C, Kumar S, Franklin BS, Dierkes T, Brinkschulte R, Tejera D, Vieira-Saecker A, Schwartz S, Santarelli F, Kummer MP, Griep A, Gelpi E, Beilharz M, Riedel D, Golenbock DT, Geyer M, Walter J, Latz E, Heneka MT. Venegas C, et al. Among authors: geyer m. Nature. 2017 Dec 20;552(7685):355-361. doi: 10.1038/nature25158. Nature. 2017. PMID: 29293211
Alternative splicing regulates stochastic NLRP3 activity.
Hoss F, Mueller JL, Rojas Ringeling F, Rodriguez-Alcazar JF, Brinkschulte R, Seifert G, Stahl R, Broderick L, Putnam CD, Kolodner RD, Canzar S, Geyer M, Hoffman HM, Latz E. Hoss F, et al. Among authors: geyer m. Nat Commun. 2019 Jul 19;10(1):3238. doi: 10.1038/s41467-019-11076-1. Nat Commun. 2019. PMID: 31324763 Free PMC article.
β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia.
Friker LL, Scheiblich H, Hochheiser IV, Brinkschulte R, Riedel D, Latz E, Geyer M, Heneka MT. Friker LL, et al. Among authors: geyer m. Cell Rep. 2020 Mar 17;30(11):3743-3754.e6. doi: 10.1016/j.celrep.2020.02.025. Cell Rep. 2020. PMID: 32187546 Free PMC article.
Development of Fluorescent and Biotin Probes Targeting NLRP3.
Keuler T, Gatterdam K, Akbal A, Lovotti M, Marleaux M, Geyer M, Latz E, Gütschow M. Keuler T, et al. Among authors: geyer m. Front Chem. 2021 Apr 22;9:642273. doi: 10.3389/fchem.2021.642273. eCollection 2021. Front Chem. 2021. PMID: 33996748 Free PMC article.
P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection.
Jenster LM, Lange KE, Normann S, vom Hemdt A, Wuerth JD, Schiffelers LDJ, Tesfamariam YM, Gohr FN, Klein L, Kaltheuner IH, Ebner S, Lapp DJ, Mayer J, Moecking J, Ploegh HL, Latz E, Meissner F, Geyer M, Kümmerer BM, Schmidt FI. Jenster LM, et al. Among authors: geyer m. J Exp Med. 2023 Jan 2;220(1):e20220837. doi: 10.1084/jem.20220837. Epub 2022 Oct 31. J Exp Med. 2023. PMID: 36315050 Free PMC article.
1,084 results