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In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.
Nature. 2021 Jan;589(7843):608-614. doi: 10.1038/s41586-020-03086-7. Epub 2021 Jan 6.
Nature. 2021.
PMID: 33408413
Free PMC article.
Mechanisms of angiogenic incompetence in Hutchinson-Gilford progeria via downregulation of endothelial NOS.
Gete YG, Koblan LW, Mao X, Trappio M, Mahadik B, Fisher JP, Liu DR, Cao K.
Gete YG, et al.
Aging Cell. 2021 Jul;20(7):e13388. doi: 10.1111/acel.13388. Epub 2021 Jun 4.
Aging Cell. 2021.
PMID: 34086398
Free PMC article.
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Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome.
Mao X, Xiong ZM, Xue H, Brown MA, Gete YG, Yu R, Sun L, Cao K.
Mao X, et al. Among authors: gete yg.
Int J Mol Sci. 2022 May 14;23(10):5499. doi: 10.3390/ijms23105499.
Int J Mol Sci. 2022.
PMID: 35628310
Free PMC article.
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Lamin A and microtubules collaborate to maintain nuclear morphology.
Tariq Z, Zhang H, Chia-Liu A, Shen Y, Gete Y, Xiong ZM, Tocheny C, Campanello L, Wu D, Losert W, Cao K.
Tariq Z, et al.
Nucleus. 2017 Jul 4;8(4):433-446. doi: 10.1080/19491034.2017.1320460. Epub 2017 May 30.
Nucleus. 2017.
PMID: 28557611
Free PMC article.
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iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome.
Atchison L, Abutaleb NO, Snyder-Mounts E, Gete Y, Ladha A, Ribar T, Cao K, Truskey GA.
Atchison L, et al.
Stem Cell Reports. 2020 Feb 11;14(2):325-337. doi: 10.1016/j.stemcr.2020.01.005. Epub 2020 Feb 6.
Stem Cell Reports. 2020.
PMID: 32032552
Free PMC article.
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An acetyl-methyl switch drives a conformational change in p53.
Tong Q, Mazur SJ, Rincon-Arano H, Rothbart SB, Kuznetsov DM, Cui G, Liu WH, Gete Y, Klein BJ, Jenkins L, Mer G, Kutateladze AG, Strahl BD, Groudine M, Appella E, Kutateladze TG.
Tong Q, et al.
Structure. 2015 Feb 3;23(2):322-31. doi: 10.1016/j.str.2014.12.010.
Structure. 2015.
PMID: 25651062
Free PMC article.
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