Geschwindner S - Search Results

1

Molecular architecture of potassium chloride co-transporter KCC2.

Agez M, Schultz P, Medina I, Baker DJ, Burnham MP, Cardarelli RA, Conway LC, Garnier K, Geschwindner S, Gunnarsson A, McCall EJ, Frechard A, Audebert S, Deeb TZ, Moss SJ, Brandon NJ, Wang Q, Dekker N, Jawhari A. Agez M, et al. Among authors: geschwindner s. Sci Rep. 2017 Nov 28;7(1):16452. doi: 10.1038/s41598-017-15739-1. Sci Rep. 2017. PMID: 29184062 Free PMC article.

2

Development of a plate-based optical biosensor fragment screening methodology to identify phosphodiesterase 10A inhibitors.

Geschwindner S, Dekker N, Horsefield R, Tigerström A, Johansson P, Scott CW, Albert JS. Geschwindner S, et al. J Med Chem. 2013 Apr 25;56(8):3228-34. doi: 10.1021/jm301665y. Epub 2013 Apr 9. J Med Chem. 2013. PMID: 23509991

3

Drug discovery at the single molecule level: inhibition-in-solution assay of membrane-reconstituted β-secretase using single-molecule imaging.

Gunnarsson A, Snijder A, Hicks J, Gunnarsson J, Höök F, Geschwindner S. Gunnarsson A, et al. Among authors: geschwindner s. Anal Chem. 2015 Apr 21;87(8):4100-3. doi: 10.1021/acs.analchem.5b00740. Epub 2015 Apr 10. Anal Chem. 2015. PMID: 25855499

4

Preserved transmembrane protein mobility in polymer-supported lipid bilayers derived from cell membranes.

Pace H, Simonsson Nyström L, Gunnarsson A, Eck E, Monson C, Geschwindner S, Snijder A, Höök F. Pace H, et al. Among authors: geschwindner s. Anal Chem. 2015 Sep 15;87(18):9194-203. doi: 10.1021/acs.analchem.5b01449. Epub 2015 Aug 24. Anal Chem. 2015. PMID: 26268463

5

Equilibrium-fluctuation analysis for interaction studies between natural ligands and single G protein-coupled receptors in native lipid vesicles.

Wahlsten O, Gunnarsson A, Simonsson Nyström L, Pace H, Geschwindner S, Höök F. Wahlsten O, et al. Among authors: geschwindner s. Langmuir. 2015 Oct 6;31(39):10774-80. doi: 10.1021/acs.langmuir.5b02463. Epub 2015 Sep 30. Langmuir. 2015. PMID: 26347379

6

Affinity Capturing and Surface Enrichment of a Membrane Protein Embedded in a Continuous Supported Lipid Bilayer.

Gunnarsson A, Simonsson Nyström L, Burazerovic S, Gunnarsson J, Snijder A, Geschwindner S, Höök F. Gunnarsson A, et al. Among authors: geschwindner s. ChemistryOpen. 2016 Aug 22;5(5):445-449. doi: 10.1002/open.201600070. eCollection 2016 Oct. ChemistryOpen. 2016. PMID: 27777836 Free PMC article.

7

Harnessing the Versatility of Optical Biosensors for Target-Based Small-Molecule Drug Discovery.

Kaminski T, Gunnarsson A, Geschwindner S. Kaminski T, et al. Among authors: geschwindner s. ACS Sens. 2017 Jan 27;2(1):10-15. doi: 10.1021/acssensors.6b00735. Epub 2016 Dec 23. ACS Sens. 2017. PMID: 28722441

8

X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors.

Witten MR, Wissler L, Snow M, Geschwindner S, Read JA, Brandon NJ, Nairn AC, Lombroso PJ, Käck H, Ellman JA. Witten MR, et al. Among authors: geschwindner s. J Med Chem. 2017 Nov 22;60(22):9299-9319. doi: 10.1021/acs.jmedchem.7b01292. Epub 2017 Nov 8. J Med Chem. 2017. PMID: 29116812 Free PMC article.

9

Regenerable Biosensors for Small-Molecule Kinetic Characterization Using SPR.

Gunnarsson A, Stubbs CJ, Rawlins PB, Taylor-Newman E, Lee WC, Geschwindner S, Hytönen V, Holdgate G, Jha R, Dahl G. Gunnarsson A, et al. Among authors: geschwindner s. SLAS Discov. 2021 Jun;26(5):730-739. doi: 10.1177/2472555220975358. Epub 2020 Dec 8. SLAS Discov. 2021. PMID: 33289457 Free article.

10

Biosensor-Enabled Deconvolution of the Avidity-Induced Affinity Enhancement for the SARS-CoV-2 Spike Protein and ACE2 Interaction.

Gutgsell AR, Gunnarsson A, Forssén P, Gordon E, Fornstedt T, Geschwindner S. Gutgsell AR, et al. Among authors: geschwindner s. Anal Chem. 2022 Jan 18;94(2):1187-1194. doi: 10.1021/acs.analchem.1c04372. Epub 2021 Dec 29. Anal Chem. 2022. PMID: 34964599

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