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The integrin-linked kinase is required for chemokine-triggered high-affinity conformation of the neutrophil β2-integrin LFA-1.
Margraf A, Germena G, Drexler HCA, Rossaint J, Ludwig N, Prystaj B, Mersmann S, Thomas K, Block H, Gottschlich W, Liu C, Krenn PW, Haller H, Heitplatz B, Meyer Zu Brickwedde M, Moser M, Vestweber D, Zarbock A. Margraf A, et al. Among authors: germena g. Blood. 2020 Nov 5;136(19):2200-2205. doi: 10.1182/blood.2020004948. Blood. 2020. PMID: 32730588 Free article.
The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flow.
Stadtmann A, Germena G, Block H, Boras M, Rossaint J, Sundd P, Lefort C, Fisher CI, Buscher K, Gelschefarth B, Urzainqui A, Gerke V, Ley K, Zarbock A. Stadtmann A, et al. Among authors: germena g. J Exp Med. 2013 Oct 21;210(11):2171-80. doi: 10.1084/jem.20130664. Epub 2013 Oct 14. J Exp Med. 2013. PMID: 24127491 Free PMC article.
The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions.
Costa C, Germena G, Martin-Conte EL, Molineris I, Bosco E, Marengo S, Azzolino O, Altruda F, Ranieri VM, Hirsch E. Costa C, et al. Among authors: germena g. Blood. 2011 Jul 28;118(4):1099-108. doi: 10.1182/blood-2010-12-324756. Epub 2011 May 6. Blood. 2011. PMID: 21551229 Free article.
PI3K keeps the balance between metabolism and cancer.
Braccini L, Ciraolo E, Martini M, Pirali T, Germena G, Rolfo K, Hirsch E. Braccini L, et al. Among authors: germena g. Adv Biol Regul. 2012 Sep;52(3):389-405. doi: 10.1016/j.jbior.2012.04.002. Epub 2012 Apr 24. Adv Biol Regul. 2012. PMID: 22884032 Review.
22 results