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Additive value of [18F]PI-2620 perfusion imaging in progressive supranuclear palsy and corticobasal syndrome.
Katzdobler S, Nitschmann A, Barthel H, Bischof G, Beyer L, Marek K, Song M, Wagemann O, Palleis C, Weidinger E, Nack A, Fietzek U, Kurz C, Häckert J, Stapf T, Ferschmann C, Scheifele M, Eckenweber F, Biechele G, Franzmeier N, Dewenter A, Schönecker S, Saur D, Schroeter ML, Rumpf JJ, Rullmann M, Schildan A, Patt M, Stephens AW, van Eimeren T, Neumaier B, Drzezga A, Danek A, Classen J, Bürger K, Janowitz D, Rauchmann BS, Stöcklein S, Perneczky R, Schöberl F, Zwergal A, Höglinger GU, Bartenstein P, Villemagne V, Seibyl J, Sabri O, Levin J, Brendel M; German Imaging Initiative for Tauopathies (GII4T). Katzdobler S, et al. Eur J Nucl Med Mol Imaging. 2023 Jan;50(2):423-434. doi: 10.1007/s00259-022-05964-w. Epub 2022 Sep 14. Eur J Nucl Med Mol Imaging. 2023. PMID: 36102964 Free PMC article.
18F-PI-2620 Tau PET Improves the Imaging Diagnosis of Progressive Supranuclear Palsy.
Messerschmidt K, Barthel H, Brendel M, Scherlach C, Hoffmann KT, Rauchmann BS, Rullmann M, Marek K, Villemagne VL, Rumpf JJ, Saur D, Schroeter ML, Schildan A, Patt M, Beyer L, Song M, Palleis C, Katzdobler S, Fietzek UM, Respondek G, Scheifele M, Nitschmann A, Zach C, Barret O, Madonia J, Russell D, Stephens AW, Koglin N, Roeber S, Herms J, Bötzel K, Bartenstein P, Levin J, Seibyl JP, Höglinger G, Classen J, Sabri O; German Imaging Initiative for Tauopathies (GII4T). Messerschmidt K, et al. J Nucl Med. 2022 Nov;63(11):1754-1760. doi: 10.2967/jnumed.121.262854. Epub 2022 Apr 14. J Nucl Med. 2022. PMID: 35422444 Free PMC article.
Feasibility of short imaging protocols for [18F]PI-2620 tau-PET in progressive supranuclear palsy.
Song M, Scheifele M, Barthel H, van Eimeren T, Beyer L, Marek K, Eckenweber F, Palleis C, Kaiser L, Finze A, Kern M, Nitschmann A, Biechele G, Katzdobler S, Bischof G, Hammes J, Jessen F, Saur D, Schroeter ML, Rumpf JJ, Rullmann M, Schildan A, Patt M, Neumaier B, Stephens AW, Rauchmann BS, Perneczky R, Levin J, Classen J, Höglinger GU, Bartenstein P, Boening G, Ziegler S, Villemagne V, Drzezga A, Seibyl J, Sabri O, Brendel M; German Imaging Initiative for Tauopathies (GII4T). Song M, et al. Eur J Nucl Med Mol Imaging. 2021 Nov;48(12):3872-3885. doi: 10.1007/s00259-021-05391-3. Epub 2021 May 22. Eur J Nucl Med Mol Imaging. 2021. PMID: 34021393 Free PMC article.
Symptomatology in 4-repeat tauopathies is associated with data-driven topology of [18F]-PI-2620 tau-PET signal.
Schönecker S, Palleis C, Franzmeier N, Katzdobler S, Ferschmann C, Schuster S, Finze A, Scheifele M, Prix C, Fietzek U, Weidinger E, Nübling G, Vöglein J, Patt M, Barthel H, Sabri O, Danek A, Höglinger GU, Brendel M, Levin J; for German Imaging Initiative for Tauopathies GII4T. Schönecker S, et al. Neuroimage Clin. 2023;38:103402. doi: 10.1016/j.nicl.2023.103402. Epub 2023 Apr 11. Neuroimage Clin. 2023. PMID: 37087820 Free PMC article.
Cortical [18 F]PI-2620 Binding Differentiates Corticobasal Syndrome Subtypes.
Palleis C, Brendel M, Finze A, Weidinger E, Bötzel K, Danek A, Beyer L, Nitschmann A, Kern M, Biechele G, Rauchmann BS, Häckert J, Höllerhage M, Stephens AW, Drzezga A, van Eimeren T, Villemagne VL, Schildan A, Barthel H, Patt M, Sabri O; German Imaging Initiative for Tauopathies (GII4T); Bartenstein P, Perneczky R, Haass C, Levin J, Höglinger GU. Palleis C, et al. Mov Disord. 2021 Sep;36(9):2104-2115. doi: 10.1002/mds.28624. Epub 2021 May 5. Mov Disord. 2021. PMID: 33951244
Tau accumulation is associated with dopamine deficiency in vivo in four-repeat tauopathies.
Ferschmann C, Messerschmidt K, Gnörich J, Barthel H, Marek K, Palleis C, Katzdobler S, Stockbauer A, Fietzek U, Finze A, Biechele G, Rumpf JJ, Saur D, Schroeter ML, Rullmann M, Beyer L, Eckenweber F, Wall S, Schildan A, Patt M, Stephens A, Classen J, Bartenstein P, Seibyl J, Franzmeier N, Levin J, Höglinger GU, Sabri O, Brendel M, Scheifele M; German Imaging Initiative for Tauopathies (GII4T). Ferschmann C, et al. Eur J Nucl Med Mol Imaging. 2024 Feb 17. doi: 10.1007/s00259-024-06637-6. Online ahead of print. Eur J Nucl Med Mol Imaging. 2024. PMID: 38366196
Dual-Phase β-Amyloid PET Captures Neuronal Injury and Amyloidosis in Corticobasal Syndrome.
Schmitt J, Palleis C, Sauerbeck J, Unterrainer M, Harris S, Prix C, Weidinger E, Katzdobler S, Wagemann O, Danek A, Beyer L, Rauchmann BS, Rominger A, Simons M, Bartenstein P, Perneczky R, Haass C, Levin J, Höglinger GU, Brendel M; German Imaging Initiative for Tauopathies (GII4T). Schmitt J, et al. Front Aging Neurosci. 2021 May 13;13:661284. doi: 10.3389/fnagi.2021.661284. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34054506 Free PMC article.