Gerhart MJ - Search Results

1

TACE/ADAM17 processing of EGFR ligands indicates a role as a physiological convertase.

Lee DC, Sunnarborg SW, Hinkle CL, Myers TJ, Stevenson MY, Russell WE, Castner BJ, Gerhart MJ, Paxton RJ, Black RA, Chang A, Jackson LF. Lee DC, et al. Among authors: gerhart mj. Ann N Y Acad Sci. 2003 May;995:22-38. doi: 10.1111/j.1749-6632.2003.tb03207.x. Ann N Y Acad Sci. 2003. PMID: 12814936 Review.

2

Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability.

Sunnarborg SW, Hinkle CL, Stevenson M, Russell WE, Raska CS, Peschon JJ, Castner BJ, Gerhart MJ, Paxton RJ, Black RA, Lee DC. Sunnarborg SW, et al. Among authors: gerhart mj. J Biol Chem. 2002 Apr 12;277(15):12838-45. doi: 10.1074/jbc.M112050200. Epub 2002 Jan 31. J Biol Chem. 2002. PMID: 11823465 Free article.

3

Expression and purification of correctly processed, active human TACE catalytic domain in Saccharomyces cerevisiae.

Clarke HR, Wolfson MF, Rauch CT, Castner BJ, Huang CP, Gerhart MJ, Johnson RS, Cerretti DP, Paxton RJ, Price VL, Black RA. Clarke HR, et al. Among authors: gerhart mj. Protein Expr Purif. 1998 Jun;13(1):104-10. doi: 10.1006/prep.1998.0861. Protein Expr Purif. 1998. PMID: 9631522

4

Metalloprotease-mediated GH receptor proteolysis and GHBP shedding. Determination of extracellular domain stem region cleavage site.

Wang X, He K, Gerhart M, Huang Y, Jiang J, Paxton RJ, Yang S, Lu C, Menon RK, Black RA, Baumann G, Frank SJ. Wang X, et al. J Biol Chem. 2002 Dec 27;277(52):50510-9. doi: 10.1074/jbc.M208738200. Epub 2002 Oct 25. J Biol Chem. 2002. PMID: 12403792 Free article.

5

Reduced proteolysis of rabbit growth hormone (GH) receptor substituted with mouse GH receptor cleavage site.

Wang X, He K, Gerhart M, Jiang J, Paxton RJ, Menon RK, Black RA, Baumann G, Frank SJ. Wang X, et al. Mol Endocrinol. 2003 Oct;17(10):1931-43. doi: 10.1210/me.2003-0120. Epub 2003 Jun 26. Mol Endocrinol. 2003. PMID: 12829808

6

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.

Black RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, Wolfson MF, Castner BJ, Stocking KL, Reddy P, Srinivasan S, Nelson N, Boiani N, Schooley KA, Gerhart M, Davis R, Fitzner JN, Johnson RS, Paxton RJ, March CJ, Cerretti DP. Black RA, et al. Nature. 1997 Feb 20;385(6618):729-33. doi: 10.1038/385729a0. Nature. 1997. PMID: 9034190

7

Relaxed specificity of matrix metalloproteinases (MMPS) and TIMP insensitivity of tumor necrosis factor-alpha (TNF-alpha) production suggest the major TNF-alpha converting enzyme is not an MMP.

Black RA, Durie FH, Otten-Evans C, Miller R, Slack JL, Lynch DH, Castner B, Mohler KM, Gerhart M, Johnson RS, Itoh Y, Okada Y, Nagase H. Black RA, et al. Biochem Biophys Res Commun. 1996 Aug 14;225(2):400-5. doi: 10.1006/bbrc.1996.1186. Biochem Biophys Res Commun. 1996. PMID: 8753775

8

Direct evidence of a heterotrimeric complex of human interleukin-4 with its receptors.

Hoffman RC, Castner BJ, Gerhart M, Gibson MG, Rasmussen BD, March CJ, Weatherbee J, Tsang M, Gustchina A, Schalk-Hihi C, et al. Hoffman RC, et al. Protein Sci. 1995 Mar;4(3):382-6. doi: 10.1002/pro.5560040304. Protein Sci. 1995. PMID: 7795521 Free PMC article.

9

γ-Secretase-mediated growth hormone receptor proteolysis: mapping of the intramembranous cleavage site.

Wang X, Cowan JW, Gerhart M, Zelickson BR, Jiang J, He K, Wolfe MS, Black RA, Frank SJ. Wang X, et al. Biochem Biophys Res Commun. 2011 May 13;408(3):432-6. doi: 10.1016/j.bbrc.2011.04.041. Epub 2011 Apr 13. Biochem Biophys Res Commun. 2011. PMID: 21514282

10

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

Walczak H, Degli-Esposti MA, Johnson RS, Smolak PJ, Waugh JY, Boiani N, Timour MS, Gerhart MJ, Schooley KA, Smith CA, Goodwin RG, Rauch CT. Walczak H, et al. Among authors: gerhart mj. EMBO J. 1997 Sep 1;16(17):5386-97. doi: 10.1093/emboj/16.17.5386. EMBO J. 1997. PMID: 9311998 Free PMC article.

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