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First-in-Human Gene Therapy Trial of AAV8-hCARp.hCNGB3 in Adults and Children With CNGB3-associated Achromatopsia.
Michaelides M, Hirji N, Wong SC, Besirli CG, Zaman S, Kumaran N, Georgiadis A, Smith AJ, Ripamonti C, Gottlob I, Robson AG, Thiadens A, Henderson RH, Fleck P, Anglade E, Dong X, Capuano G, Lu W, Berry P, Kane T, Naylor S, Georgiou M, Kalitzeos A, Ali RR, Forbes A, Bainbridge J. Michaelides M, et al. Among authors: georgiadis a. Am J Ophthalmol. 2023 Sep;253:243-251. doi: 10.1016/j.ajo.2023.05.009. Epub 2023 May 11. Am J Ophthalmol. 2023. PMID: 37172884 Free article. Clinical Trial.
Stable rAAV-mediated transduction of rod and cone photoreceptors in the canine retina.
Bainbridge JW, Mistry A, Schlichtenbrede FC, Smith A, Broderick C, De Alwis M, Georgiadis A, Taylor PM, Squires M, Sethi C, Charteris D, Thrasher AJ, Sargan D, Ali RR. Bainbridge JW, et al. Among authors: georgiadis a. Gene Ther. 2003 Aug;10(16):1336-44. doi: 10.1038/sj.gt.3301990. Gene Ther. 2003. PMID: 12883530
Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis.
Broderick CA, Smith AJ, Balaggan KS, Georgiadis A, Buch PK, Trittibach PC, Barker SE, Sarra GM, Thrasher AJ, Dick AD, Ali RR. Broderick CA, et al. Among authors: georgiadis a. Mol Ther. 2005 Aug;12(2):369-73. doi: 10.1016/j.ymthe.2005.03.018. Mol Ther. 2005. PMID: 16043105 Free article.
Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina.
Gonzalez-Cordero A, West EL, Pearson RA, Duran Y, Carvalho LS, Chu CJ, Naeem A, Blackford SJI, Georgiadis A, Lakowski J, Hubank M, Smith AJ, Bainbridge JWB, Sowden JC, Ali RR. Gonzalez-Cordero A, et al. Among authors: georgiadis a. Nat Biotechnol. 2013 Aug;31(8):741-7. doi: 10.1038/nbt.2643. Epub 2013 Jul 21. Nat Biotechnol. 2013. PMID: 23873086 Free PMC article.
233 results