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Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch.
Cornel AM, Dunnebach E, Hofman DA, Das S, Sengupta S, van den Ham F, Wienke J, Strijker JGM, van den Beemt DAMH, Essing AHW, Koopmans B, Engels SAG, Lo Presti V, Szanto CS, George RE, Molenaar JJ, van Heesch S, Dierselhuis MP, Nierkens S. Cornel AM, et al. Among authors: george re. J Immunother Cancer. 2022 Dec;10(12):e005002. doi: 10.1136/jitc-2022-005002. J Immunother Cancer. 2022. PMID: 36521927 Free PMC article.
Pharmacotherapy of neuroblastoma.
George RE, Diller L, Bernstein ML. George RE, et al. Expert Opin Pharmacother. 2010 Jun;11(9):1467-78. doi: 10.1517/14656566.2010.482100. Expert Opin Pharmacother. 2010. PMID: 20408767 Review.
TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors.
Valentijn LJ, Koster J, Zwijnenburg DA, Hasselt NE, van Sluis P, Volckmann R, van Noesel MM, George RE, Tytgat GA, Molenaar JJ, Versteeg R. Valentijn LJ, et al. Among authors: george re. Nat Genet. 2015 Dec;47(12):1411-4. doi: 10.1038/ng.3438. Epub 2015 Nov 2. Nat Genet. 2015. PMID: 26523776
Super-Enhancer-Driven Transcriptional Dependencies in Cancer.
Sengupta S, George RE. Sengupta S, et al. Among authors: george re. Trends Cancer. 2017 Apr;3(4):269-281. doi: 10.1016/j.trecan.2017.03.006. Epub 2017 Apr 12. Trends Cancer. 2017. PMID: 28718439 Free PMC article. Review.
Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras.
Cohen MA, Zhang S, Sengupta S, Ma H, Bell GW, Horton B, Sharma B, George RE, Spranger S, Jaenisch R. Cohen MA, et al. Among authors: george re. Cell Stem Cell. 2020 Apr 2;26(4):579-592.e6. doi: 10.1016/j.stem.2020.02.001. Epub 2020 Mar 5. Cell Stem Cell. 2020. PMID: 32142683 Free PMC article.
Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration.
Huang H, Gont A, Kee L, Dries R, Pfeifer K, Sharma B, Debruyne DN, Harlow M, Sengupta S, Guan J, Yeung CM, Wang W, Hallberg B, Palmer RH, Irwin MS, George RE. Huang H, et al. Among authors: george re. Cell Rep. 2021 Jul 13;36(2):109363. doi: 10.1016/j.celrep.2021.109363. Cell Rep. 2021. PMID: 34260934 Free PMC article.
Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes.
Sengupta S, Das S, Crespo AC, Cornel AM, Patel AG, Mahadevan NR, Campisi M, Ali AK, Sharma B, Rowe JH, Huang H, Debruyne DN, Cerda ED, Krajewska M, Dries R, Chen M, Zhang S, Soriano L, Cohen MA, Versteeg R, Jaenisch R, Spranger S, Romee R, Miller BC, Barbie DA, Nierkens S, Dyer MA, Lieberman J, George RE. Sengupta S, et al. Among authors: george re. Nat Cancer. 2022 Oct;3(10):1228-1246. doi: 10.1038/s43018-022-00427-5. Epub 2022 Sep 22. Nat Cancer. 2022. PMID: 36138189 Free PMC article.
CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness.
Qin X, Lam A, Zhang X, Sengupta S, Iorgulescu JB, Ni H, Das S, Rager M, Zhou Z, Zuo T, Meara GK, Floru AE, Kemet C, Veerapaneni D, Kashy D, Lin L, Lloyd K, Kwok L, Smith KS, Nagaraju RT, Meijers R, Ceol C, Liu CT, Alexandrescu S, Wu CJ, Keskin DB, George RE, Feng H. Qin X, et al. Among authors: george re. Sci Adv. 2024 Mar 15;10(11):eadh9547. doi: 10.1126/sciadv.adh9547. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489372 Free PMC article.
129 results