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Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.
Griebel G, Pichat P, Beeské S, Leroy T, Redon N, Jacquet A, Françon D, Bert L, Even L, Lopez-Grancha M, Tolstykh T, Sun F, Yu Q, Brittain S, Arlt H, He T, Zhang B, Wiederschain D, Bertrand T, Houtmann J, Rak A, Vallée F, Michot N, Augé F, Menet V, Bergis OE, George P, Avenet P, Mikol V, Didier M, Escoubet J. Griebel G, et al. Among authors: george p. Sci Rep. 2015 Jan 6;5:7642. doi: 10.1038/srep07642. Sci Rep. 2015. PMID: 25560837 Free PMC article.
SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (1) binding and functional profile.
Biton B, Bergis OE, Galli F, Nedelec A, Lochead AW, Jegham S, Godet D, Lanneau C, Santamaria R, Chesney F, Léonardon J, Granger P, Debono MW, Bohme GA, Sgard F, Besnard F, Graham D, Coste A, Oblin A, Curet O, Vigé X, Voltz C, Rouquier L, Souilhac J, Santucci V, Gueudet C, Françon D, Steinberg R, Griebel G, Oury-Donat F, George P, Avenet P, Scatton B. Biton B, et al. Among authors: george p. Neuropsychopharmacology. 2007 Jan;32(1):1-16. doi: 10.1038/sj.npp.1301189. Epub 2006 Oct 4. Neuropsychopharmacology. 2007. PMID: 17019409
Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia.
Boulay D, Pichat P, Dargazanli G, Estenne-Bouhtou G, Terranova JP, Rogacki N, Stemmelin J, Coste A, Lanneau C, Desvignes C, Cohen C, Alonso R, Vigé X, Biton B, Steinberg R, Sevrin M, Oury-Donat F, George P, Bergis O, Griebel G, Avenet P, Scatton B. Boulay D, et al. Among authors: george p. Pharmacol Biochem Behav. 2008 Nov;91(1):47-58. doi: 10.1016/j.pbb.2008.06.009. Epub 2008 Jun 24. Pharmacol Biochem Behav. 2008. PMID: 18621075
Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic.
Depoortère R, Dargazanli G, Estenne-Bouhtou G, Coste A, Lanneau C, Desvignes C, Poncelet M, Heaulme M, Santucci V, Decobert M, Cudennec A, Voltz C, Boulay D, Terranova JP, Stemmelin J, Roger P, Marabout B, Sevrin M, Vigé X, Biton B, Steinberg R, Françon D, Alonso R, Avenet P, Oury-Donat F, Perrault G, Griebel G, George P, Soubrié P, Scatton B. Depoortère R, et al. Among authors: george p. Neuropsychopharmacology. 2005 Nov;30(11):1963-85. doi: 10.1038/sj.npp.1300772. Neuropsychopharmacology. 2005. PMID: 15956994
SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms.
Griebel G, Perrault G, Simiand J, Cohen C, Granger P, Depoortere H, Françon D, Avenet P, Schoemaker H, Evanno Y, Sevrin M, George P, Scatton B. Griebel G, et al. Among authors: george p. CNS Drug Rev. 2003 Spring;9(1):3-20. doi: 10.1111/j.1527-3458.2003.tb00241.x. CNS Drug Rev. 2003. PMID: 12595909 Free PMC article. Review.
SSR591813, a novel selective and partial alpha4beta2 nicotinic receptor agonist with potential as an aid to smoking cessation.
Cohen C, Bergis OE, Galli F, Lochead AW, Jegham S, Biton B, Leonardon J, Avenet P, Sgard F, Besnard F, Graham D, Coste A, Oblin A, Curet O, Voltz C, Gardes A, Caille D, Perrault G, George P, Soubrie P, Scatton B. Cohen C, et al. Among authors: george p. J Pharmacol Exp Ther. 2003 Jul;306(1):407-20. doi: 10.1124/jpet.103.049262. Epub 2003 Apr 7. J Pharmacol Exp Ther. 2003. PMID: 12682217
SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist. I: Neurochemical and electrophysiological profile.
Claustre Y, Peretti DD, Brun P, Gueudet C, Allouard N, Alonso R, Lourdelet J, Oblin A, Damoiseau G, Françon D, Suaud-Chagny MF, Steinberg R, Sevrin M, Schoemaker H, George P, Soubrié P, Scatton B. Claustre Y, et al. Among authors: george p. Neuropsychopharmacology. 2003 Dec;28(12):2064-76. doi: 10.1038/sj.npp.1300262. Neuropsychopharmacology. 2003. PMID: 12902994
1,604 results