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SARS-CoV-2-specific T cell therapy for severe COVID-19: a randomized phase 1/2 trial.
Papadopoulou A, Karavalakis G, Papadopoulou E, Xochelli A, Bousiou Z, Vogiatzoglou A, Papayanni PG, Georgakopoulou A, Giannaki M, Stavridou F, Vallianou I, Kammenou M, Varsamoudi E, Papadimitriou V, Giannaki C, Sileli M, Stergiouda Z, Stefanou G, Kourlaba G, Gounelas G, Triantafyllidou M, Siotou E, Karaglani A, Zotou E, Chatzika G, Boukla A, Papalexandri A, Koutra MG, Apostolou D, Pitsiou G, Morfesis P, Doumas M, Karampatakis T, Kapravelos N, Bitzani M, Theodorakopoulou M, Serasli E, Georgolopoulos G, Sakellari I, Fylaktou A, Tryfon S, Anagnostopoulos A, Yannaki E. Papadopoulou A, et al. Among authors: georgakopoulou a. Nat Med. 2023 Aug;29(8):2019-2029. doi: 10.1038/s41591-023-02480-8. Epub 2023 Jul 17. Nat Med. 2023. PMID: 37460756 Clinical Trial.
Vaccinated and Convalescent Donor-Derived Severe Acute Respiratory Syndrome Coronavirus 2-Specific T Cells as Adoptive Immunotherapy for High-Risk Coronavirus Disease 2019 Patients.
Papayanni PG, Chasiotis D, Koukoulias K, Georgakopoulou A, Iatrou A, Gavriilaki E, Giannaki C, Bitzani M, Geka E, Tasioudis P, Chloros D, Fylaktou A, Kioumis I, Triantafyllidou M, Dimou-Besikli S, Karavalakis G, Boutou AK, Siotou E, Anagnostopoulos A, Papadopoulou A, Yannaki E. Papayanni PG, et al. Among authors: georgakopoulou a. Clin Infect Dis. 2021 Dec 6;73(11):2073-2082. doi: 10.1093/cid/ciab371. Clin Infect Dis. 2021. PMID: 33905481 Free PMC article.
"Cerberus" T Cells: A Glucocorticoid-Resistant, Multi-Pathogen Specific T Cell Product to Fight Infections in Severely Immunocompromised Patients.
Koukoulias K, Papayanni PG, Georgakopoulou A, Alvanou M, Laidou S, Kouimtzidis A, Pantazi C, Gkoliou G, Vyzantiadis TA, Spyridonidis A, Makris A, Chatzidimitriou A, Psatha N, Anagnostopoulos A, Yannaki E, Papadopoulou A. Koukoulias K, et al. Among authors: georgakopoulou a. Front Immunol. 2021 Jan 18;11:608701. doi: 10.3389/fimmu.2020.608701. eCollection 2020. Front Immunol. 2021. PMID: 33537032 Free PMC article.
In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.
Wang H, Georgakopoulou A, Psatha N, Li C, Capsali C, Samal HB, Anagnostopoulos A, Ehrhardt A, Izsvák Z, Papayannopoulou T, Yannaki E, Lieber A. Wang H, et al. Among authors: georgakopoulou a. J Clin Invest. 2019 Feb 1;129(2):598-615. doi: 10.1172/JCI122836. Epub 2018 Dec 18. J Clin Invest. 2019. PMID: 30422819 Free PMC article.
Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors.
Li C, Wang H, Gil S, Germond A, Fountain C, Baldessari A, Kim J, Liu Z, Georgakopoulou A, Radtke S, Raskó T, Pande A, Chiang C, Chin E, Yannaki E, Izsvák Z, Papayannopoulou T, Kiem HP, Lieber A. Li C, et al. Among authors: georgakopoulou a. Mol Ther Methods Clin Dev. 2021 Dec 6;24:127-141. doi: 10.1016/j.omtm.2021.12.003. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2021. PMID: 35036470 Free PMC article.
In vivo HSC prime editing rescues sickle cell disease in a mouse model.
Li C, Georgakopoulou A, Newby GA, Chen PJ, Everette KA, Paschoudi K, Vlachaki E, Gil S, Anderson AK, Koob T, Huang L, Wang H, Kiem HP, Liu DR, Yannaki E, Lieber A. Li C, et al. Among authors: georgakopoulou a. Blood. 2023 Apr 27;141(17):2085-2099. doi: 10.1182/blood.2022018252. Blood. 2023. PMID: 36800642 Free PMC article.
26 results