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New developments in RiPP discovery, enzymology and engineering.
Montalbán-López M, Scott TA, Ramesh S, Rahman IR, van Heel AJ, Viel JH, Bandarian V, Dittmann E, Genilloud O, Goto Y, Grande Burgos MJ, Hill C, Kim S, Koehnke J, Latham JA, Link AJ, Martínez B, Nair SK, Nicolet Y, Rebuffat S, Sahl HG, Sareen D, Schmidt EW, Schmitt L, Severinov K, Süssmuth RD, Truman AW, Wang H, Weng JK, van Wezel GP, Zhang Q, Zhong J, Piel J, Mitchell DA, Kuipers OP, van der Donk WA. Montalbán-López M, et al. Among authors: genilloud o. Nat Prod Rep. 2021 Jan 1;38(1):130-239. doi: 10.1039/d0np00027b. Epub 2020 Sep 16. Nat Prod Rep. 2021. PMID: 32935693 Free PMC article. Review.
Cacaoidin, First Member of the New Lanthidin RiPP Family.
Ortiz-López FJ, Carretero-Molina D, Sánchez-Hidalgo M, Martín J, González I, Román-Hurtado F, de la Cruz M, García-Fernández S, Reyes F, Deisinger JP, Müller A, Schneider T, Genilloud O. Ortiz-López FJ, et al. Among authors: genilloud o. Angew Chem Int Ed Engl. 2020 Jul 27;59(31):12654-12658. doi: 10.1002/anie.202005187. Epub 2020 Jun 15. Angew Chem Int Ed Engl. 2020. PMID: 32407589
Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: genilloud o. Nat Rev Chem. 2021;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 34426795 Free PMC article. Review.
Total Synthesis and Biosynthesis of Cyclodepsipeptide Cochinmicin I.
Schnegotzki R, Wiebach V, Sánchez-Hidalgo M, Tietzmann M, Zur Bonsen AB, Genilloud O, Süssmuth RD. Schnegotzki R, et al. Among authors: genilloud o. Org Lett. 2022 Apr 1;24(12):2344-2348. doi: 10.1021/acs.orglett.2c00525. Epub 2022 Mar 21. Org Lett. 2022. PMID: 35311291
Mechanistic Studies on Dehydration in Class V Lanthipeptides.
Liang H, Lopez IJ, Sánchez-Hidalgo M, Genilloud O, van der Donk WA. Liang H, et al. Among authors: genilloud o. ACS Chem Biol. 2022 Sep 16;17(9):2519-2527. doi: 10.1021/acschembio.2c00458. Epub 2022 Aug 31. ACS Chem Biol. 2022. PMID: 36044589 Free PMC article.
181 results