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Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration.
Vighi E, Trifunović D, Veiga-Crespo P, Rentsch A, Hoffmann D, Sahaboglu A, Strasser T, Kulkarni M, Bertolotti E, van den Heuvel A, Peters T, Reijerkerk A, Euler T, Ueffing M, Schwede F, Genieser HG, Gaillard P, Marigo V, Ekström P, Paquet-Durand F. Vighi E, et al. Among authors: genieser hg. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2997-E3006. doi: 10.1073/pnas.1718792115. Epub 2018 Mar 12. Proc Natl Acad Sci U S A. 2018. PMID: 29531030 Free PMC article.
New cGMP analogues restrain proliferation and migration of melanoma cells.
Vighi E, Rentsch A, Henning P, Comitato A, Hoffmann D, Bertinetti D, Bertolotti E, Schwede F, Herberg FW, Genieser HG, Marigo V. Vighi E, et al. Among authors: genieser hg. Oncotarget. 2017 Dec 25;9(4):5301-5320. doi: 10.18632/oncotarget.23685. eCollection 2018 Jan 12. Oncotarget. 2017. PMID: 29435180 Free PMC article.
Epac-Rap signaling reduces cellular stress and ischemia-induced kidney failure.
Stokman G, Qin Y, Genieser HG, Schwede F, de Heer E, Bos JL, Bajema IM, van de Water B, Price LS. Stokman G, et al. Among authors: genieser hg. J Am Soc Nephrol. 2011 May;22(5):859-72. doi: 10.1681/ASN.2010040423. Epub 2011 Apr 14. J Am Soc Nephrol. 2011. PMID: 21493776 Free PMC article.
Activation of PDE10 and PDE11 phosphodiesterases.
Jäger R, Russwurm C, Schwede F, Genieser HG, Koesling D, Russwurm M. Jäger R, et al. Among authors: genieser hg. J Biol Chem. 2012 Jan 6;287(2):1210-9. doi: 10.1074/jbc.M111.263806. Epub 2011 Nov 21. J Biol Chem. 2012. PMID: 22105073 Free PMC article.
67 results