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Patient Endothelial Colony-Forming Cells to Model Coronary Artery Disease Susceptibility and Unravel the Role of Dysregulated Mitochondrial Redox Signalling.
Antioxidants (Basel). 2021 Sep 29;10(10):1547. doi: 10.3390/antiox10101547.
Antioxidants (Basel). 2021.
PMID: 34679682
Free PMC article.
The novel P2X7 receptor antagonist PKT100 improves cardiac function and survival in pulmonary hypertension by direct targeting of the right ventricle.
Hansen T, Karimi Galougahi K, Besnier M, Genetzakis E, Tsang M, Finemore M, O'Brien-Brown J, Di Bartolo BA, Kassiou M, Bubb KJ, Figtree GA.
Hansen T, et al. Among authors: genetzakis e.
Am J Physiol Heart Circ Physiol. 2020 Jul 1;319(1):H183-H191. doi: 10.1152/ajpheart.00580.2019. Epub 2020 May 29.
Am J Physiol Heart Circ Physiol. 2020.
PMID: 32469637
Free article.
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Development and clinical translation of P2X7 receptor antagonists: A potential therapeutic target in coronary artery disease?
Genetzakis E, Gilchrist J, Kassiou M, Figtree GA.
Genetzakis E, et al.
Pharmacol Ther. 2022 Sep;237:108228. doi: 10.1016/j.pharmthera.2022.108228. Epub 2022 Jun 16.
Pharmacol Ther. 2022.
PMID: 35716953
Review.
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High-Throughput Measure of Mitochondrial Superoxide Levels as a Marker of Coronary Artery Disease to Accelerate Drug Translation in Patient-Derived Endothelial Cells Using Opera Phenix® Technology.
Lee WE, Besnier M, Genetzakis E, Tang O, Kott KA, Vernon ST, Gray MP, Grieve SM, Kassiou M, Figtree GA.
Lee WE, et al. Among authors: genetzakis e.
Int J Mol Sci. 2023 Dec 19;25(1):22. doi: 10.3390/ijms25010022.
Int J Mol Sci. 2023.
PMID: 38203193
Free PMC article.
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Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art Review.
Figtree GA, Vernon ST, Harmer JA, Gray MP, Arnott C, Bachour E, Barsha G, Brieger D, Brown A, Celermajer DS, Channon KM, Chew NWS, Chong JJH, Chow CK, Cistulli PA, Ellinor PT, Grieve SM, Guzik TJ, Hagström E, Jenkins A, Jennings G, Keech AC, Kott KA, Kritharides L, Mamas MA, Mehran R, Meikle PJ, Natarajan P, Negishi K, O'Sullivan J, Patel S, Psaltis PJ, Redfern J, Steg PG, Sullivan DR, Sundström J, Vogel B, Wilson A, Wong D, Bhatt DL, Kovacic JC, Nicholls SJ; CRE for CAD Collaborators.
Figtree GA, et al.
J Am Coll Cardiol. 2023 Sep 26;82(13):1343-1359. doi: 10.1016/j.jacc.2023.06.045.
J Am Coll Cardiol. 2023.
PMID: 37730292
Free PMC article.
Review.
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Serum Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 (sLOX-1) Is Associated with Atherosclerosis Severity in Coronary Artery Disease.
Kott KA, Genetzakis E, Gray MP, Hansen P, McGuire HM, Yang JY, Grieve SM, Vernon ST, Figtree GA.
Kott KA, et al. Among authors: genetzakis e.
Biomolecules. 2023 Jul 29;13(8):1187. doi: 10.3390/biom13081187.
Biomolecules. 2023.
PMID: 37627252
Free PMC article.
Item in Clipboard
Novel Strategies in the Early Detection and Treatment of Endothelial Cell-Specific Mitochondrial Dysfunction in Coronary Artery Disease.
Lee WE, Genetzakis E, Figtree GA.
Lee WE, et al. Among authors: genetzakis e.
Antioxidants (Basel). 2023 Jun 28;12(7):1359. doi: 10.3390/antiox12071359.
Antioxidants (Basel). 2023.
PMID: 37507899
Free PMC article.
Review.
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