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Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.
Ma L, Sahu SK, Cano M, Kuppuswamy V, Bajwa J, McPhatter J, Pine A, Meizlish M, Goshua G, Chang CH, Zhang H, Price C, Bahel P, Rinder H, Lei T, Day A, Reynolds D, Wu X, Schriefer R, Rauseo AM, Goss CW, O'Halloran JA, Presti RM, Kim AH, Gelman AE, Cruz CD, Lee AI, Mudd P, Chun HJ, Atkinson JP, Kulkarni HS. Ma L, et al. Among authors: gelman ae. bioRxiv [Preprint]. 2021 Feb 23:2021.02.22.432177. doi: 10.1101/2021.02.22.432177. bioRxiv. 2021. PMID: 33655244 Free PMC article. Updated. Preprint.
Local complement activation is associated with primary graft dysfunction after lung transplantation.
Kulkarni HS, Ramphal K, Ma L, Brown M, Oyster M, Speckhart KN, Takahashi T, Byers DE, Porteous MK, Kalman L, Hachem RR, Rushefski M, McPhatter J, Cano M, Kreisel D, Scavuzzo M, Mittler B, Cantu E 3rd, Pilely K, Garred P, Christie JD, Atkinson JP, Gelman AE, Diamond JM. Kulkarni HS, et al. Among authors: gelman ae. JCI Insight. 2020 Sep 3;5(17):e138358. doi: 10.1172/jci.insight.138358. JCI Insight. 2020. PMID: 32750037 Free PMC article.
Circulating Mitochondrial DNA is an Early Indicator of Severe Illness and Mortality from COVID-19.
Scozzi D, Cano M, Ma L, Zhou D, Zhu JH, O'Halloran JA, Goss C, Rauseo AM, Liu Z, Peritore V, Rocco M, Ricci A, Amodeo R, Aimati L, Ibrahim M, Hachem R, Kreisel D, Mudd PA, Kulkarni HS, Gelman AE. Scozzi D, et al. Among authors: gelman ae. bioRxiv [Preprint]. 2020 Jul 30:2020.07.30.227553. doi: 10.1101/2020.07.30.227553. bioRxiv. 2020. PMID: 32766574 Free PMC article. Updated. Preprint.
Circulating mitochondrial DNA is an early indicator of severe illness and mortality from COVID-19.
Scozzi D, Cano M, Ma L, Zhou D, Zhu JH, O'Halloran JA, Goss C, Rauseo AM, Liu Z, Sahu SK, Peritore V, Rocco M, Ricci A, Amodeo R, Aimati L, Ibrahim M, Hachem R, Kreisel D, Mudd PA, Kulkarni HS, Gelman AE. Scozzi D, et al. Among authors: gelman ae. JCI Insight. 2021 Feb 22;6(4):e143299. doi: 10.1172/jci.insight.143299. JCI Insight. 2021. PMID: 33444289 Free PMC article.
Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury.
Sahu SK, Ozantürk AN, Kulkarni DH, Ma L, Barve RA, Dannull L, Lu A, Starick M, McPhatter J, Garnica L, Sanfillipo-Burchman M, Kunen J, Wu X, Gelman AE, Brody SL, Atkinson JP, Kulkarni HS. Sahu SK, et al. Among authors: gelman ae. Sci Immunol. 2023 Feb 3;8(80):eabp9547. doi: 10.1126/sciimmunol.abp9547. Epub 2023 Feb 3. Sci Immunol. 2023. PMID: 36735773 Free PMC article.
Reprogramming alveolar macrophage responses to TGF-β reveals CCR2+ monocyte activity that promotes bronchiolitis obliterans syndrome.
Liu Z, Liao F, Zhu J, Zhou D, Heo GS, Leuhmann HP, Scozzi D, Parks A, Hachem R, Byers DE, Tague LK, Kulkarni HS, Cano M, Wong BW, Li W, Huang HJ, Krupnick AS, Kreisel D, Liu Y, Gelman AE. Liu Z, et al. Among authors: gelman ae. J Clin Invest. 2022 Oct 3;132(19):e159229. doi: 10.1172/JCI159229. J Clin Invest. 2022. PMID: 36189800 Free PMC article.
Nanoparticle targeting of neutrophil glycolysis prevents lung ischemia-reperfusion injury.
Liao F, Scozzi D, Zhou D, Maksimos M, Diedrich C, Cano M, Tague LK, Liu Z, Haspel JA, Leonard JM, Li W, Krupnick AS, Wong BW, Kreisel D, Azab AK, Gelman AE. Liao F, et al. Among authors: gelman ae. Am J Transplant. 2024 Mar 24:S1600-6135(24)00238-7. doi: 10.1016/j.ajt.2024.03.028. Online ahead of print. Am J Transplant. 2024. PMID: 38522826
Pseudomonas aeruginosa and acute rejection independently increase the risk of donor-specific antibodies after lung transplantation.
Kulkarni HS, Tsui K, Sunder S, Ganninger A, Tague LK, Witt CA, Byers DE, Trulock EP, Nava R, Puri V, Kreisel D, Mohanakumar T, Gelman AE, Hachem RR. Kulkarni HS, et al. Among authors: gelman ae. Am J Transplant. 2020 Apr;20(4):1028-1038. doi: 10.1111/ajt.15687. Epub 2019 Dec 24. Am J Transplant. 2020. PMID: 31677358 Free PMC article.
159 results