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Page 1
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.
Altea-Manzano P, Doglioni G, Liu Y, Cuadros AM, Nolan E, Fernández-García J, Wu Q, Planque M, Laue KJ, Cidre-Aranaz F, Liu XZ, Marin-Bejar O, Van Elsen J, Vermeire I, Broekaert D, Demeyer S, Spotbeen X, Idkowiak J, Montagne A, Demicco M, Alkan HF, Rabas N, Riera-Domingo C, Richard F, Geukens T, De Schepper M, Leduc S, Hatse S, Lambrechts Y, Kay EJ, Lilla S, Alekseenko A, Geldhof V, Boeckx B, de la Calle Arregui C, Floris G, Swinnen JV, Marine JC, Lambrechts D, Pelechano V, Mazzone M, Zanivan S, Cools J, Wildiers H, Baud V, Grünewald TGP, Ben-David U, Desmedt C, Malanchi I, Fendt SM. Altea-Manzano P, et al. Among authors: geldhof v. Nat Cancer. 2023 Mar;4(3):344-364. doi: 10.1038/s43018-023-00513-2. Epub 2023 Feb 2. Nat Cancer. 2023. PMID: 36732635 Free PMC article.
Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast.
Geldhof V, de Rooij LPMH, Sokol L, Amersfoort J, De Schepper M, Rohlenova K, Hoste G, Vanderstichele A, Delsupehe AM, Isnaldi E, Dai N, Taverna F, Khan S, Truong AK, Teuwen LA, Richard F, Treps L, Smeets A, Nevelsteen I, Weynand B, Vinckier S, Schoonjans L, Kalucka J, Desmedt C, Neven P, Mazzone M, Floris G, Punie K, Dewerchin M, Eelen G, Wildiers H, Li X, Luo Y, Carmeliet P. Geldhof V, et al. Nat Commun. 2022 Sep 20;13(1):5511. doi: 10.1038/s41467-022-33052-y. Nat Commun. 2022. PMID: 36127427 Free PMC article.
The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution.
de Rooij LPMH, Becker LM, Teuwen LA, Boeckx B, Jansen S, Feys S, Verleden S, Liesenborghs L, Stalder AK, Libbrecht S, Van Buyten T, Philips G, Subramanian A, Dumas SJ, Meta E, Borri M, Sokol L, Dendooven A, Truong AK, Gunst J, Van Mol P, Haslbauer JD, Rohlenova K, Menter T, Boudewijns R, Geldhof V, Vinckier S, Amersfoort J, Wuyts W, Van Raemdonck D, Jacobs W, Ceulemans LJ, Weynand B, Thienpont B, Lammens M, Kuehnel M, Eelen G, Dewerchin M, Schoonjans L, Jonigk D, van Dorpe J, Tzankov A, Wauters E, Mazzone M, Neyts J, Wauters J, Lambrechts D, Carmeliet P. de Rooij LPMH, et al. Among authors: geldhof v. Cardiovasc Res. 2023 Mar 31;119(2):520-535. doi: 10.1093/cvr/cvac139. Cardiovasc Res. 2023. PMID: 35998078 Free PMC article.
Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle.
Conchinha NV, Sokol L, Teuwen LA, Veys K, Dumas SJ, Meta E, García-Caballero M, Geldhof V, Chen R, Treps L, Borri M, de Zeeuw P, Falkenberg KD, Dubois C, Parys M, de Rooij LPMH, Rohlenova K, Goveia J, Schoonjans L, Dewerchin M, Eelen G, Li X, Kalucka J, Carmeliet P. Conchinha NV, et al. Among authors: geldhof v. STAR Protoc. 2021 Sep 14;2(3):100508. doi: 10.1016/j.xpro.2021.100508. eCollection 2021 Sep 17. STAR Protoc. 2021. PMID: 34585146 Free PMC article.
Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis.
Dumas SJ, Meta E, Conchinha NV, Sokol L, Chen R, Borri M, Teuwen LA, Veys K, García-Caballero M, Geldhof V, Treps L, de Zeeuw P, Falkenberg KD, Dubois C, Parys M, de Rooij LPMH, Rohlenova K, Goveia J, Schoonjans L, Dewerchin M, Eelen G, Li X, Kalucka J, Carmeliet P. Dumas SJ, et al. Among authors: geldhof v. STAR Protoc. 2021 Jul 28;2(3):100523. doi: 10.1016/j.xpro.2021.100523. eCollection 2021 Sep 17. STAR Protoc. 2021. PMID: 34382011 Free PMC article.
Corrigendum to "itraconazole for COVID-19: Preclinical studies and a proof-of-concept randomized clinical trial Laurens".
Liesenborghs L, Spriet I, Jochmans D, Belmans A, Gyselinck I, Teuwen LA, Ter Horst S, Dreesen E, Geukens T, Engelen MM, Landeloos E, Geldhof V, Ceunen H, Debaveye B, Vandenberk B, Van der Linden L, Jacobs S, Langendries L, Boudewijns R, Dan Do TN, Chiu W, Wang X, Zhang X, Weynand B, Vanassche T, Devos T, Meyfroidt G, Janssens W, Vos R, Vermeersch P, Wauters J, Verbeke G, De Munter P, Kaptein SJF, Rocha-Pereira J, Delang L, Van Wijngaerden E, Neyts J, Verhamme P. Liesenborghs L, et al. Among authors: geldhof v. EBioMedicine. 2021 Jul;69:103454. doi: 10.1016/j.ebiom.2021.103454. Epub 2021 Jun 26. EBioMedicine. 2021. PMID: 34186486 Free PMC article. No abstract available.
Tumor vessel co-option probed by single-cell analysis.
Teuwen LA, De Rooij LPMH, Cuypers A, Rohlenova K, Dumas SJ, García-Caballero M, Meta E, Amersfoort J, Taverna F, Becker LM, Veiga N, Cantelmo AR, Geldhof V, Conchinha NV, Kalucka J, Treps L, Conradi LC, Khan S, Karakach TK, Soenen S, Vinckier S, Schoonjans L, Eelen G, Van Laere S, Dewerchin M, Dirix L, Mazzone M, Luo Y, Vermeulen P, Carmeliet P. Teuwen LA, et al. Among authors: geldhof v. Cell Rep. 2021 Jun 15;35(11):109253. doi: 10.1016/j.celrep.2021.109253. Cell Rep. 2021. PMID: 34133923 Free article.
Protocols for endothelial cell isolation from mouse tissues: small intestine, colon, heart, and liver.
Sokol L, Geldhof V, García-Caballero M, Conchinha NV, Dumas SJ, Meta E, Teuwen LA, Veys K, Chen R, Treps L, Borri M, de Zeeuw P, Falkenberg KD, Dubois C, Parys M, de Rooij LPMH, Goveia J, Rohlenova K, Schoonjans L, Dewerchin M, Eelen G, Li X, Kalucka J, Carmeliet P. Sokol L, et al. Among authors: geldhof v. STAR Protoc. 2021 May 1;2(2):100489. doi: 10.1016/j.xpro.2021.100489. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 34007969 Free PMC article.
Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trial.
Liesenborghs L, Spriet I, Jochmans D, Belmans A, Gyselinck I, Teuwen LA, Ter Horst S, Dreesen E, Geukens T, Engelen MM, Landeloos E, Geldhof V, Ceunen H, Debaveye B, Vandenberk B, Van der Linden L, Jacobs S, Langendries L, Boudewijns R, Do TND, Chiu W, Wang X, Zhang X, Weynand B, Vanassche T, Devos T, Meyfroidt G, Janssens W, Vos R, Vermeersch P, Wauters J, Verbeke G, De Munter P, Kaptein SJF, Rocha-Pereira J, Delang L, Van Wijngaerden E, Neyts J, Verhamme P. Liesenborghs L, et al. Among authors: geldhof v. EBioMedicine. 2021 Apr;66:103288. doi: 10.1016/j.ebiom.2021.103288. Epub 2021 Mar 19. EBioMedicine. 2021. PMID: 33752127 Free PMC article. Clinical Trial.
In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition.
Rinaldi G, Pranzini E, Van Elsen J, Broekaert D, Funk CM, Planque M, Doglioni G, Altea-Manzano P, Rossi M, Geldhof V, Teoh ST, Ross C, Hunter KW, Lunt SY, Grünewald TGP, Fendt SM. Rinaldi G, et al. Among authors: geldhof v. Mol Cell. 2021 Jan 21;81(2):386-397.e7. doi: 10.1016/j.molcel.2020.11.027. Epub 2020 Dec 18. Mol Cell. 2021. PMID: 33340488 Free PMC article.
25 results