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The histone demethylase Jarid1b mediates angiotensin II-induced endothelial dysfunction by controlling the 3'UTR of soluble epoxide hydrolase.
Vasconez AE, Janetzko P, Oo JA, Pflüger-Müller B, Ratiu C, Gu L, Helin K, Geisslinger G, Fleming I, Schröder K, Fork C, Brandes RP, Leisegang MS. Vasconez AE, et al. Among authors: geisslinger g. Acta Physiol (Oxf). 2019 Jan;225(1):e13168. doi: 10.1111/apha.13168. Epub 2018 Aug 25. Acta Physiol (Oxf). 2019. PMID: 30076673
Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice.
Revermann M, Schloss M, Barbosa-Sicard E, Mieth A, Liebner S, Morisseau C, Geisslinger G, Schermuly RT, Fleming I, Hammock BD, Brandes RP. Revermann M, et al. Among authors: geisslinger g. Arterioscler Thromb Vasc Biol. 2010 May;30(5):909-14. doi: 10.1161/ATVBAHA.110.204099. Epub 2010 Mar 11. Arterioscler Thromb Vasc Biol. 2010. PMID: 20224052 Free PMC article.
A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm.
Revermann M, Mieth A, Popescu L, Paulke A, Wurglics M, Pellowska M, Fischer AS, Steri R, Maier TJ, Schermuly RT, Geisslinger G, Schubert-Zsilavecz M, Brandes RP, Steinhilber D. Revermann M, et al. Among authors: geisslinger g. Br J Pharmacol. 2011 Aug;163(8):1721-32. doi: 10.1111/j.1476-5381.2011.01321.x. Br J Pharmacol. 2011. PMID: 21410457 Free PMC article.
Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation.
Brenneis C, Sisignano M, Coste O, Altenrath K, Fischer MJ, Angioni C, Fleming I, Brandes RP, Reeh PW, Woolf CJ, Geisslinger G, Scholich K. Brenneis C, et al. Among authors: geisslinger g. Mol Pain. 2011 Oct 4;7:78. doi: 10.1186/1744-8069-7-78. Mol Pain. 2011. PMID: 21970373 Free PMC article.
NADPH oxidase-4 maintains neuropathic pain after peripheral nerve injury.
Kallenborn-Gerhardt W, Schröder K, Del Turco D, Lu R, Kynast K, Kosowski J, Niederberger E, Shah AM, Brandes RP, Geisslinger G, Schmidtko A. Kallenborn-Gerhardt W, et al. Among authors: geisslinger g. J Neurosci. 2012 Jul 25;32(30):10136-45. doi: 10.1523/JNEUROSCI.6227-11.2012. J Neurosci. 2012. PMID: 22836249 Free PMC article.
598 results