Geismann C - Search Results

1

Monocarboxylate Transporter-1 (MCT1)-Mediated Lactate Uptake Protects Pancreatic Adenocarcinoma Cells from Oxidative Stress during Glutamine Scarcity Thereby Promoting Resistance against Inhibitors of Glutamine Metabolism.

Ammar N, Hildebrandt M, Geismann C, Röder C, Gemoll T, Sebens S, Trauzold A, Schäfer H. Ammar N, et al. Among authors: geismann c. Antioxidants (Basel). 2023 Sep 30;12(10):1818. doi: 10.3390/antiox12101818. Antioxidants (Basel). 2023. PMID: 37891897 Free PMC article.

2

Inflammatory macrophages induce Nrf2 transcription factor-dependent proteasome activity in colonic NCM460 cells and thereby confer anti-apoptotic protection.

Sebens S, Bauer I, Geismann C, Grage-Griebenow E, Ehlers S, Kruse ML, Arlt A, Schäfer H. Sebens S, et al. Among authors: geismann c. J Biol Chem. 2011 Nov 25;286(47):40911-21. doi: 10.1074/jbc.M111.274902. Epub 2011 Oct 11. J Biol Chem. 2011. PMID: 21990354 Free PMC article.

3

Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress.

Stachel I, Geismann C, Aden K, Deisinger F, Rosenstiel P, Schreiber S, Sebens S, Arlt A, Schäfer H. Stachel I, et al. Among authors: geismann c. J Biol Chem. 2014 Jan 24;289(4):1917-29. doi: 10.1074/jbc.M113.490920. Epub 2013 Dec 5. J Biol Chem. 2014. PMID: 24311782 Free PMC article.

4

Cytoprotection "gone astray": Nrf2 and its role in cancer.

Geismann C, Arlt A, Sebens S, Schäfer H. Geismann C, et al. Onco Targets Ther. 2014 Aug 26;7:1497-518. doi: 10.2147/OTT.S36624. eCollection 2014. Onco Targets Ther. 2014. PMID: 25210464 Free PMC article. Review.

5

c-Rel is a critical mediator of NF-κB-dependent TRAIL resistance of pancreatic cancer cells.

Geismann C, Grohmann F, Sebens S, Wirths G, Dreher A, Häsler R, Rosenstiel P, Hauser C, Egberts JH, Trauzold A, Schneider G, Sipos B, Zeissig S, Schreiber S, Schäfer H, Arlt A. Geismann C, et al. Cell Death Dis. 2014 Oct 9;5(10):e1455. doi: 10.1038/cddis.2014.417. Cell Death Dis. 2014. PMID: 25299780 Free PMC article.

6

Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent.

Schäfer H, Geismann C, Heneweer C, Egberts JH, Korniienko O, Kiefel H, Moldenhauer G, Bachem MG, Kalthoff H, Altevogt P, Sebens S. Schäfer H, et al. Among authors: geismann c. Carcinogenesis. 2012 Jan;33(1):84-93. doi: 10.1093/carcin/bgr262. Epub 2011 Nov 17. Carcinogenesis. 2012. PMID: 22095073

7

Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity.

Arlt A, Sebens S, Krebs S, Geismann C, Grossmann M, Kruse ML, Schreiber S, Schäfer H. Arlt A, et al. Among authors: geismann c. Oncogene. 2013 Oct;32(40):4825-35. doi: 10.1038/onc.2012.493. Epub 2012 Oct 29. Oncogene. 2013. PMID: 23108405

8

Binding of the transcription factor Slug to the L1CAM promoter is essential for transforming growth factor-β1 (TGF-β)-induced L1CAM expression in human pancreatic ductal adenocarcinoma cells.

Geismann C, Arlt A, Bauer I, Pfeifer M, Schirmer U, Altevogt P, Müerköster SS, Schäfer H. Geismann C, et al. Int J Oncol. 2011 Jan;38(1):257-66. Int J Oncol. 2011. PMID: 21109948

9

TGF-β1-dependent L1CAM expression has an essential role in macrophage-induced apoptosis resistance and cell migration of human intestinal epithelial cells.

Schäfer H, Struck B, Feldmann EM, Bergmann F, Grage-Griebenow E, Geismann C, Ehlers S, Altevogt P, Sebens S. Schäfer H, et al. Among authors: geismann c. Oncogene. 2013 Jan 10;32(2):180-9. doi: 10.1038/onc.2012.44. Epub 2012 Feb 20. Oncogene. 2013. PMID: 22349829

10

NF-κB Dependent Chemokine Signaling in Pancreatic Cancer.

Geismann C, Schäfer H, Gundlach JP, Hauser C, Egberts JH, Schneider G, Arlt A. Geismann C, et al. Cancers (Basel). 2019 Sep 26;11(10):1445. doi: 10.3390/cancers11101445. Cancers (Basel). 2019. PMID: 31561620 Free PMC article. Review.

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