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Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
Martinelli S, Anderzhanova EA, Bajaj T, Wiechmann S, Dethloff F, Weckmann K, Heinz DE, Ebert T, Hartmann J, Geiger TM, Döngi M, Hafner K, Pöhlmann ML, Jollans L, Philipsen A, Schmidt SV, Schmidt U, Maccarrone G, Stein V, Hausch F, Turck CW, Schmidt MV, Gellner AK, Kuster B, Gassen NC. Martinelli S, et al. Among authors: geiger tm. Nat Commun. 2021 Jul 30;12(1):4643. doi: 10.1038/s41467-021-24810-5. Nat Commun. 2021. PMID: 34330919 Free PMC article.
Macrocyclic FKBP51 Ligands Define a Transient Binding Mode with Enhanced Selectivity.
Voll AM, Meyners C, Taubert MC, Bajaj T, Heymann T, Merz S, Charalampidou A, Kolos J, Purder PL, Geiger TM, Wessig P, Gassen NC, Bracher A, Hausch F. Voll AM, et al. Among authors: geiger tm. Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13257-13263. doi: 10.1002/anie.202017352. Epub 2021 May 7. Angew Chem Int Ed Engl. 2021. PMID: 33843131 Free PMC article.
FKBP51 and FKBP12.6-Novel and tight interactors of Glomulin.
Hähle A, Geiger TM, Merz S, Meyners C, Tianqi M, Kolos J, Hausch F. Hähle A, et al. Among authors: geiger tm. PLoS One. 2019 Sep 6;14(9):e0221926. doi: 10.1371/journal.pone.0221926. eCollection 2019. PLoS One. 2019. PMID: 31490997 Free PMC article.
Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides.
Kolos JM, Pomplun S, Jung S, Rieß B, Purder PL, Voll AM, Merz S, Gnatzy M, Geiger TM, Quist-Løkken I, Jatzlau J, Knaus P, Holien T, Bracher A, Meyners C, Czodrowski P, Krewald V, Hausch F. Kolos JM, et al. Among authors: geiger tm. Chem Sci. 2021 Nov 3;12(44):14758-14765. doi: 10.1039/d1sc04638a. eCollection 2021 Nov 17. Chem Sci. 2021. PMID: 34820091 Free PMC article.
Modulating the Electronic and Solid-State Structure of Organic Semiconductors by Site-Specific Substitution: The Case of Tetrafluoropentacenes.
Geiger T, Schundelmeier S, Hummel T, Ströbele M, Leis W, Seitz M, Zeiser C, Moretti L, Maiuri M, Cerullo G, Broch K, Vahland J, Leo K, Maichle-Mössmer C, Speiser B, Bettinger HF. Geiger T, et al. Chemistry. 2020 Mar 12;26(15):3420-3434. doi: 10.1002/chem.201905843. Epub 2020 Feb 25. Chemistry. 2020. PMID: 31985891 Free PMC article.
80 results