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Impaired immune surveillance accelerates accumulation of senescent cells and aging.
Ovadya Y, Landsberger T, Leins H, Vadai E, Gal H, Biran A, Yosef R, Sagiv A, Agrawal A, Shapira A, Windheim J, Tsoory M, Schirmbeck R, Amit I, Geiger H, Krizhanovsky V. Ovadya Y, et al. Among authors: geiger h. Nat Commun. 2018 Dec 21;9(1):5435. doi: 10.1038/s41467-018-07825-3. Nat Commun. 2018. PMID: 30575733 Free PMC article.
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
Florian MC, Nattamai KJ, Dörr K, Marka G, Uberle B, Vas V, Eckl C, Andrä I, Schiemann M, Oostendorp RA, Scharffetter-Kochanek K, Kestler HA, Zheng Y, Geiger H. Florian MC, et al. Among authors: geiger h. Nature. 2013 Nov 21;503(7476):392-6. doi: 10.1038/nature12631. Epub 2013 Oct 20. Nature. 2013. PMID: 24141946 Free PMC article.
Hematopoietic stem cell aging.
Geiger H, Denkinger M, Schirmbeck R. Geiger H, et al. Curr Opin Immunol. 2014 Aug;29:86-92. doi: 10.1016/j.coi.2014.05.002. Epub 2014 Jun 3. Curr Opin Immunol. 2014. PMID: 24905894 Review.
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.
Walter D, Lier A, Geiselhart A, Thalheimer FB, Huntscha S, Sobotta MC, Moehrle B, Brocks D, Bayindir I, Kaschutnig P, Muedder K, Klein C, Jauch A, Schroeder T, Geiger H, Dick TP, Holland-Letz T, Schmezer P, Lane SW, Rieger MA, Essers MA, Williams DA, Trumpp A, Milsom MD. Walter D, et al. Among authors: geiger h. Nature. 2015 Apr 23;520(7548):549-52. doi: 10.1038/nature14131. Epub 2015 Feb 18. Nature. 2015. PMID: 25707806
HSC Aging and Senescent Immune Remodeling.
Denkinger MD, Leins H, Schirmbeck R, Florian MC, Geiger H. Denkinger MD, et al. Among authors: geiger h. Trends Immunol. 2015 Dec;36(12):815-824. doi: 10.1016/j.it.2015.10.008. Epub 2015 Nov 21. Trends Immunol. 2015. PMID: 26611154 Free PMC article. Review.
630 results