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ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers.
Augustyn A, Borromeo M, Wang T, Fujimoto J, Shao C, Dospoy PD, Lee V, Tan C, Sullivan JP, Larsen JE, Girard L, Behrens C, Wistuba II, Xie Y, Cobb MH, Gazdar AF, Johnson JE, Minna JD. Augustyn A, et al. Among authors: gazdar af. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14788-93. doi: 10.1073/pnas.1410419111. Epub 2014 Sep 29. Proc Natl Acad Sci U S A. 2014. PMID: 25267614 Free PMC article.
Small cell lung cancers made from scratch.
Gazdar AF, Minna JD. Gazdar AF, et al. J Exp Med. 2019 Mar 4;216(3):476-478. doi: 10.1084/jem.20182216. Epub 2019 Feb 13. J Exp Med. 2019. PMID: 30760489 Free PMC article.
Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer.
Cai L, Liu H, Huang F, Fujimoto J, Girard L, Chen J, Li Y, Zhang YA, Deb D, Stastny V, Pozo K, Kuo CS, Jia G, Yang C, Zou W, Alomar A, Huffman K, Papari-Zareei M, Yang L, Drapkin B, Akbay EA, Shames DS, Wistuba II, Wang T, Johnson JE, Xiao G, DeBerardinis RJ, Minna JD, Xie Y, Gazdar AF. Cai L, et al. Among authors: gazdar af. Commun Biol. 2021 Mar 9;4(1):314. doi: 10.1038/s42003-021-01842-7. Commun Biol. 2021. PMID: 33750914 Free PMC article.
Targeted therapies for killing tumor cells.
Gazdar AF, Minna JD. Gazdar AF, et al. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10028-30. doi: 10.1073/pnas.191379998. Proc Natl Acad Sci U S A. 2001. PMID: 11526225 Free PMC article. No abstract available.
779 results