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HIF Prolyl Hydroxylase Inhibitors for COVID-19 Treatment: Pros and Cons.
Poloznikov AA, Nersisyan SA, Hushpulian DM, Kazakov EH, Tonevitsky AG, Kazakov SV, Vechorko VI, Nikulin SV, Makarova JA, Gazaryan IG. Poloznikov AA, et al. Among authors: gazaryan ig. Front Pharmacol. 2021 Jan 29;11:621054. doi: 10.3389/fphar.2020.621054. eCollection 2020. Front Pharmacol. 2021. PMID: 33584306 Free PMC article. Review.
Neuroprotective Effect of HIF Prolyl Hydroxylase Inhibition in an In Vitro Hypoxia Model.
Savyuk M, Krivonosov M, Mishchenko T, Gazaryan I, Ivanchenko M, Khristichenko A, Poloznikov A, Hushpulian D, Nikulin S, Tonevitsky E, Abuzarova G, Mitroshina E, Vedunova M. Savyuk M, et al. Among authors: gazaryan i. Antioxidants (Basel). 2020 Jul 24;9(8):662. doi: 10.3390/antiox9080662. Antioxidants (Basel). 2020. PMID: 32722310 Free PMC article.
Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors.
Gaisina IN, Lee SH, Kaidery NA, Ben Aissa M, Ahuja M, Smirnova NN, Wakade S, Gaisin A, Bourassa MW, Ratan RR, Nikulin SV, Poloznikov AA, Thomas B, Thatcher GRJ, Gazaryan IG. Gaisina IN, et al. ACS Chem Neurosci. 2018 May 16;9(5):894-900. doi: 10.1021/acschemneuro.7b00435. Epub 2018 Jan 17. ACS Chem Neurosci. 2018. PMID: 29338172 Free PMC article.
Structure-Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors.
Poloznikov AA, Nikulin SV, Hushpulian DM, Khristichenko AY, Osipyants AI, Asachenko AF, Shurupova OV, Savin SS, Lee SH, Gaisina IN, Thatcher GRJ, Narciso A, Chang EP, Kazakov SV, Krucher N, Tishkov VI, Thomas B, Gazaryan IG. Poloznikov AA, et al. Among authors: gazaryan ig. Antioxidants (Basel). 2022 Jan 24;11(2):220. doi: 10.3390/antiox11020220. Antioxidants (Basel). 2022. PMID: 35204103 Free PMC article.
Bach1 derepression is neuroprotective in a mouse model of Parkinson's disease.
Ahuja M, Ammal Kaidery N, Attucks OC, McDade E, Hushpulian DM, Gaisin A, Gaisina I, Ahn YH, Nikulin S, Poloznikov A, Gazaryan I, Yamamoto M, Matsumoto M, Igarashi K, Sharma SM, Thomas B. Ahuja M, et al. Among authors: gazaryan i. Proc Natl Acad Sci U S A. 2021 Nov 9;118(45):e2111643118. doi: 10.1073/pnas.2111643118. Proc Natl Acad Sci U S A. 2021. PMID: 34737234 Free PMC article.
74 results