Gawlik K - Search Results

1

HCV core residues critical for infectivity are also involved in core-NS5A complex formation.

Gawlik K, Baugh J, Chatterji U, Lim PJ, Bobardt MD, Gallay PA. Gawlik K, et al. PLoS One. 2014 Feb 12;9(2):e88866. doi: 10.1371/journal.pone.0088866. eCollection 2014. PLoS One. 2014. PMID: 24533158 Free PMC article.

2

HCV core protein and virus assembly: what we know without structures.

Gawlik K, Gallay PA. Gawlik K, et al. Immunol Res. 2014 Oct;60(1):1-10. doi: 10.1007/s12026-014-8494-3. Immunol Res. 2014. PMID: 24557493 Free PMC article. Review.

3

The combination of alisporivir plus an NS5A inhibitor provides additive to synergistic anti-hepatitis C virus activity without detectable cross-resistance.

Chatterji U, Garcia-Rivera JA, Baugh J, Gawlik K, Wong KA, Zhong W, Brass CA, Naoumov NV, Gallay PA. Chatterji U, et al. Among authors: gawlik k. Antimicrob Agents Chemother. 2014 Jun;58(6):3327-34. doi: 10.1128/AAC.00016-14. Epub 2014 Mar 31. Antimicrob Agents Chemother. 2014. PMID: 24687498 Free PMC article.

4

Both Cyclophilin Inhibitors and Direct-Acting Antivirals Prevent PKR Activation in HCV-Infected Cells.

Bobardt M, Chatterji U, Lim P, Gawlik K, Gallay P. Bobardt M, et al. Among authors: gawlik k. Open Virol J. 2014 Mar 7;8:1-8. doi: 10.2174/1874357901408010001. eCollection 2014. Open Virol J. 2014. PMID: 24799968 Free PMC article.

5

Autocatalytic activation of the furin zymogen requires removal of the emerging enzyme's N-terminus from the active site.

Gawlik K, Shiryaev SA, Zhu W, Motamedchaboki K, Desjardins R, Day R, Remacle AG, Stec B, Strongin AY. Gawlik K, et al. PLoS One. 2009;4(4):e5031. doi: 10.1371/journal.pone.0005031. Epub 2009 Apr 7. PLoS One. 2009. PMID: 19352504 Free PMC article.

6

A femtomol range FRET biosensor reports exceedingly low levels of cell surface furin: implications for the processing of anthrax protective antigen.

Gawlik K, Remacle AG, Shiryaev SA, Golubkov VS, Ouyang M, Wang Y, Strongin AY. Gawlik K, et al. PLoS One. 2010 Jun 24;5(6):e11305. doi: 10.1371/journal.pone.0011305. PLoS One. 2010. PMID: 20585585 Free PMC article. Retracted.

7

Proteolysis of the membrane type-1 matrix metalloproteinase prodomain: implications for a two-step proteolytic processing and activation.

Golubkov VS, Chekanov AV, Shiryaev SA, Aleshin AE, Ratnikov BI, Gawlik K, Radichev I, Motamedchaboki K, Smith JW, Strongin AY. Golubkov VS, et al. Among authors: gawlik k. J Biol Chem. 2007 Dec 14;282(50):36283-91. doi: 10.1074/jbc.M706290200. Epub 2007 Oct 15. J Biol Chem. 2007. PMID: 17938169 Free article.

8

Isolation and characterization of selective and potent human Fab inhibitors directed to the active-site region of the two-component NS2B-NS3 proteinase of West Nile virus.

Shiryaev SA, Radichev IA, Ratnikov BI, Aleshin AE, Gawlik K, Stec B, Frisch C, Knappik A, Strongin AY. Shiryaev SA, et al. Among authors: gawlik k. Biochem J. 2010 Apr 14;427(3):369-76. doi: 10.1042/BJ20100074. Biochem J. 2010. PMID: 20156198 Free PMC article.

9

Virtual ligand screening of the National Cancer Institute (NCI) compound library leads to the allosteric inhibitory scaffolds of the West Nile Virus NS3 proteinase.

Shiryaev SA, Cheltsov AV, Gawlik K, Ratnikov BI, Strongin AY. Shiryaev SA, et al. Among authors: gawlik k. Assay Drug Dev Technol. 2011 Feb;9(1):69-78. doi: 10.1089/adt.2010.0309. Epub 2010 Nov 4. Assay Drug Dev Technol. 2011. PMID: 21050032 Free PMC article.

10

Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis.

Shiryaev SA, Remacle AG, Savinov AY, Chernov AV, Cieplak P, Radichev IA, Williams R, Shiryaeva TN, Gawlik K, Postnova TI, Ratnikov BI, Eroshkin AM, Motamedchaboki K, Smith JW, Strongin AY. Shiryaev SA, et al. Among authors: gawlik k. J Biol Chem. 2009 Oct 30;284(44):30615-26. doi: 10.1074/jbc.M109.041244. Epub 2009 Sep 2. J Biol Chem. 2009. PMID: 19726693 Free PMC article.

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