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AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A.
Gautier B, Hajjar H, Soares S, Berthelot J, Deck M, Abbou S, Campbell G, Ceprian M, Gonzalez S, Fovet CM, Schütza V, Jouvenel A, Rivat C, Zerah M, François V, Le Guiner C, Aubourg P, Fledrich R, Tricaud N. Gautier B, et al. Nat Commun. 2021 Apr 21;12(1):2356. doi: 10.1038/s41467-021-22593-3. Nat Commun. 2021. PMID: 33883545 Free PMC article.
Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells.
Deck M, Van Hameren G, Campbell G, Bernard-Marissal N, Devaux J, Berthelot J, Lattard A, Médard JJ, Gautier B, Guelfi S, Abbou S, Quintana P, Chao de la Barca JM, Reynier P, Lenaers G, Chrast R, Tricaud N. Deck M, et al. Among authors: gautier b. PLoS One. 2022 Oct 4;17(10):e0272097. doi: 10.1371/journal.pone.0272097. eCollection 2022. PLoS One. 2022. PMID: 36194565 Free PMC article.
Intracerebral Gene Therapy Using AAVrh.10-hARSA Recombinant Vector to Treat Patients with Early-Onset Forms of Metachromatic Leukodystrophy: Preclinical Feasibility and Safety Assessments in Nonhuman Primates.
Zerah M, Piguet F, Colle MA, Raoul S, Deschamps JY, Deniaud J, Gautier B, Toulgoat F, Bieche I, Laurendeau I, Sondhi D, Souweidane MM, Cartier-Lacave N, Moullier P, Crystal RG, Roujeau T, Sevin C, Aubourg P. Zerah M, et al. Among authors: gautier b. Hum Gene Ther Clin Dev. 2015 Jun;26(2):113-24. doi: 10.1089/humc.2014.139. Epub 2015 Apr 28. Hum Gene Ther Clin Dev. 2015. PMID: 25758611 Clinical Trial.
67 results