Gautam P - Search Results

1

Endothelial destabilization by angiopoietin-2 via integrin β1 activation.

Hakanpaa L, Sipila T, Leppanen VM, Gautam P, Nurmi H, Jacquemet G, Eklund L, Ivaska J, Alitalo K, Saharinen P. Hakanpaa L, et al. Among authors: gautam p. Nat Commun. 2015 Jan 30;6:5962. doi: 10.1038/ncomms6962. Nat Commun. 2015. PMID: 25635707 Free PMC article.

2

Donor simvastatin treatment prevents ischemia-reperfusion and acute kidney injury by preserving microvascular barrier function.

Tuuminen R, Nykänen AI, Saharinen P, Gautam P, Keränen MA, Arnaudova R, Rouvinen E, Helin H, Tammi R, Rilla K, Krebs R, Lemström KB. Tuuminen R, et al. Among authors: gautam p. Am J Transplant. 2013 Aug;13(8):2019-34. doi: 10.1111/ajt.12315. Epub 2013 Jun 14. Am J Transplant. 2013. PMID: 23773358 Free article.

3

Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects.

Julkunen H, Cichonska A, Gautam P, Szedmak S, Douat J, Pahikkala T, Aittokallio T, Rousu J. Julkunen H, et al. Among authors: gautam p. Nat Commun. 2020 Dec 1;11(1):6136. doi: 10.1038/s41467-020-19950-z. Nat Commun. 2020. PMID: 33262326 Free PMC article.

4

A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening.

Gupta A, Gautam P, Wennerberg K, Aittokallio T. Gupta A, et al. Among authors: gautam p. Commun Biol. 2020 Jan 23;3(1):42. doi: 10.1038/s42003-020-0765-z. Commun Biol. 2020. PMID: 31974521 Free PMC article.

5

Prediction of drug combination effects with a minimal set of experiments.

Ianevski A, Giri AK, Gautam P, Kononov A, Potdar S, Saarela J, Wennerberg K, Aittokallio T. Ianevski A, et al. Among authors: gautam p. Nat Mach Intell. 2019 Dec;1(12):568-577. doi: 10.1038/s42256-019-0122-4. Epub 2019 Dec 9. Nat Mach Intell. 2019. PMID: 32368721 Free PMC article.

6

Consistency in drug response profiling.

Mpindi JP, Yadav B, Östling P, Gautam P, Malani D, Murumägi A, Hirasawa A, Kangaspeska S, Wennerberg K, Kallioniemi O, Aittokallio T. Mpindi JP, et al. Among authors: gautam p. Nature. 2016 Nov 30;540(7631):E5-E6. doi: 10.1038/nature20171. Nature. 2016. PMID: 27905421 No abstract available.

7

Multiobjective optimization identifies cancer-selective combination therapies.

Pulkkinen OI, Gautam P, Mustonen V, Aittokallio T. Pulkkinen OI, et al. Among authors: gautam p. PLoS Comput Biol. 2020 Dec 28;16(12):e1008538. doi: 10.1371/journal.pcbi.1008538. eCollection 2020 Dec. PLoS Comput Biol. 2020. PMID: 33370253 Free PMC article.

8

Systematic mapping of cancer cell target dependencies using high-throughput drug screening in triple-negative breast cancer.

Wang T, Gautam P, Rousu J, Aittokallio T. Wang T, et al. Among authors: gautam p. Comput Struct Biotechnol J. 2020 Nov 24;18:3819-3832. doi: 10.1016/j.csbj.2020.11.001. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 33335681 Free PMC article.

9

Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells.

Gautam P, Karhinen L, Szwajda A, Jha SK, Yadav B, Aittokallio T, Wennerberg K. Gautam P, et al. Mol Cancer. 2016 May 10;15(1):34. doi: 10.1186/s12943-016-0517-3. Mol Cancer. 2016. PMID: 27165605 Free PMC article.

10

Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets.

Gautam P, Jaiswal A, Aittokallio T, Al-Ali H, Wennerberg K. Gautam P, et al. Cell Chem Biol. 2019 Jul 18;26(7):970-979.e4. doi: 10.1016/j.chembiol.2019.03.011. Epub 2019 May 2. Cell Chem Biol. 2019. PMID: 31056464 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

460 results

Search Page