Gaudio E - Search Results

1

The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type.

Tarantelli C, Cannas E, Ekeh H, Moscatello C, Gaudio E, Cascione L, Napoli S, Rech C, Testa A, Maniaci C, Rinaldi A, Zucca E, Stathis A, Ciulli A, Bertoni F. Tarantelli C, et al. Among authors: gaudio e. Explor Target Antitumor Ther. 2021;2(6):586-601. doi: 10.37349/etat.2021.00065. Epub 2021 Dec 31. Explor Target Antitumor Ther. 2021. PMID: 36046113 Free PMC article.

2

Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma.

Chilà R, Basana A, Lupi M, Guffanti F, Gaudio E, Rinaldi A, Cascione L, Restelli V, Tarantelli C, Bertoni F, Damia G, Carrassa L. Chilà R, et al. Among authors: gaudio e. Oncotarget. 2015 Feb 20;6(5):3394-408. doi: 10.18632/oncotarget.2583. Oncotarget. 2015. PMID: 25428911 Free PMC article.

3

The BET Bromodomain Inhibitor OTX015 Affects Pathogenetic Pathways in Preclinical B-cell Tumor Models and Synergizes with Targeted Drugs.

Boi M, Gaudio E, Bonetti P, Kwee I, Bernasconi E, Tarantelli C, Rinaldi A, Testoni M, Cascione L, Ponzoni M, Mensah AA, Stathis A, Stussi G, Riveiro ME, Herait P, Inghirami G, Cvitkovic E, Zucca E, Bertoni F. Boi M, et al. Among authors: gaudio e. Clin Cancer Res. 2015 Apr 1;21(7):1628-38. doi: 10.1158/1078-0432.CCR-14-1561. Epub 2015 Jan 26. Clin Cancer Res. 2015. PMID: 25623213

4

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response.

Mensah AA, Kwee I, Gaudio E, Rinaldi A, Ponzoni M, Cascione L, Fossati G, Stathis A, Zucca E, Caprini G, Bertoni F. Mensah AA, et al. Among authors: gaudio e. Oncotarget. 2015 Mar 10;6(7):5059-71. doi: 10.18632/oncotarget.3239. Oncotarget. 2015. PMID: 25671298 Free PMC article.

5

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor.

Vesci L, Bernasconi E, Milazzo FM, De Santis R, Gaudio E, Kwee I, Rinaldi A, Pace S, Carollo V, Giannini G, Bertoni F. Vesci L, et al. Among authors: gaudio e. Oncotarget. 2015 Mar 20;6(8):5735-48. doi: 10.18632/oncotarget.3240. Oncotarget. 2015. PMID: 25671299 Free PMC article.

6

The novel atypical retinoid ST5589 down-regulates Aurora Kinase A and has anti-tumour activity in lymphoma pre-clinical models.

Bernasconi E, Gaudio E, Kwee I, Rinaldi A, Cascione L, Tarantelli C, Mensah AA, Stathis A, Zucca E, Vesci L, Giannini G, Bertoni F. Bernasconi E, et al. Among authors: gaudio e. Br J Haematol. 2015 Nov;171(3):378-86. doi: 10.1111/bjh.13595. Epub 2015 Aug 3. Br J Haematol. 2015. PMID: 26235926 Free article.

7

Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas.

Gaudio E, Tarantelli C, Kwee I, Barassi C, Bernasconi E, Rinaldi A, Ponzoni M, Cascione L, Targa A, Stathis A, Goodstal S, Zucca E, Bertoni F. Gaudio E, et al. Ann Oncol. 2016 Jun;27(6):1123-1128. doi: 10.1093/annonc/mdw131. Epub 2016 Mar 8. Ann Oncol. 2016. PMID: 26961147 Free article.

8

Assessment of the Antiproliferative Activity of a BET Bromodomain Inhibitor as Single Agent and in Combination in Non-Hodgkin Lymphoma Cell Lines.

Bernasconi E, Gaudio E, Kwee I, Bertoni F. Bernasconi E, et al. Among authors: gaudio e. Methods Mol Biol. 2016;1436:305-12. doi: 10.1007/978-1-4939-3667-0_20. Methods Mol Biol. 2016. PMID: 27246223

9

Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma.

Gaudio E, Tarantelli C, Ponzoni M, Odore E, Rezai K, Bernasconi E, Cascione L, Rinaldi A, Stathis A, Riveiro E, Cvitkovic E, Zucca E, Bertoni F. Gaudio E, et al. Oncotarget. 2016 Sep 6;7(36):58142-58147. doi: 10.18632/oncotarget.10983. Oncotarget. 2016. PMID: 27494885 Free PMC article.

10

Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma.

Bernasconi E, Gaudio E, Lejeune P, Tarantelli C, Cascione L, Kwee I, Spriano F, Rinaldi A, Mensah AA, Chung E, Stathis A, Siegel S, Schmees N, Ocker M, Zucca E, Haendler B, Bertoni F. Bernasconi E, et al. Among authors: gaudio e. Br J Haematol. 2017 Sep;178(6):936-948. doi: 10.1111/bjh.14803. Epub 2017 Jun 27. Br J Haematol. 2017. PMID: 28653353 Free article.

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