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Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Prévost J, Chen Y, Zhou F, Tolbert WD, Gasser R, Medjahed H, Nayrac M, Nguyen DN, Gottumukkala S, Hessell AJ, Rao VB, Pozharski E, Huang RK, Matthies D, Finzi A, Pazgier M. Prévost J, et al. Among authors: gasser r. Nat Commun. 2023 Oct 23;14(1):6710. doi: 10.1038/s41467-023-42500-2. Nat Commun. 2023. PMID: 37872202 Free PMC article.
Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells.
Richard J, Nguyen DN, Tolbert WD, Gasser R, Ding S, Vézina D, Yu Gong S, Prévost J, Gendron-Lepage G, Medjahed H, Gottumukkala S, Finzi A, Pazgier M. Richard J, et al. Among authors: gasser r. mBio. 2021 Oct 26;12(5):e0140521. doi: 10.1128/mBio.01405-21. Epub 2021 Sep 28. mBio. 2021. PMID: 34579568 Free PMC article.
Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern.
Li W, Chen Y, Prévost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vézina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Côté M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W. Li W, et al. Among authors: gasser r. Cell Rep. 2022 Jan 11;38(2):110210. doi: 10.1016/j.celrep.2021.110210. Epub 2021 Dec 15. Cell Rep. 2022. PMID: 34971573 Free PMC article.
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection.
Beaudoin-Bussières G, Chen Y, Ullah I, Prévost J, Tolbert WD, Symmes K, Ding S, Benlarbi M, Gong SY, Tauzin A, Gasser R, Chatterjee D, Vézina D, Goyette G, Richard J, Zhou F, Stamatatos L, McGuire AT, Charest H, Roger M, Pozharski E, Kumar P, Mothes W, Uchil PD, Pazgier M, Finzi A. Beaudoin-Bussières G, et al. Among authors: gasser r. Cell Rep. 2022 Feb 15;38(7):110368. doi: 10.1016/j.celrep.2022.110368. Epub 2022 Jan 25. Cell Rep. 2022. PMID: 35123652 Free PMC article.
Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD.
Chen Y, Prévost J, Ullah I, Romero H, Lisi V, Tolbert WD, Grover JR, Ding S, Gong SY, Beaudoin-Bussières G, Gasser R, Benlarbi M, Vézina D, Anand SP, Chatterjee D, Goyette G, Grunst MW, Yang Z, Bo Y, Zhou F, Béland K, Bai X, Zeher AR, Huang RK, Nguyen DN, Sherburn R, Wu D, Piszczek G, Paré B, Matthies D, Xia D, Richard J, Kumar P, Mothes W, Côté M, Uchil PD, Lavallée VP, Smith MA, Pazgier M, Haddad E, Finzi A. Chen Y, et al. Among authors: gasser r. iScience. 2023 Jan 20;26(1):105783. doi: 10.1016/j.isci.2022.105783. Epub 2022 Dec 9. iScience. 2023. PMID: 36514310 Free PMC article.
Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity.
Laumaea A, Marchitto L, Ding S, Beaudoin-Bussières G, Prévost J, Gasser R, Chatterjee D, Gendron-Lepage G, Medjahed H, Chen HC, Smith AB 3rd, Ding H, Kappes JC, Hahn BH, Kirchhoff F, Richard J, Duerr R, Finzi A. Laumaea A, et al. Among authors: gasser r. Cell Rep. 2023 Jan 31;42(1):111983. doi: 10.1016/j.celrep.2022.111983. Epub 2023 Jan 10. Cell Rep. 2023. PMID: 36640355 Free PMC article.
Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals.
Beaudoin-Bussières G, Laumaea A, Anand SP, Prévost J, Gasser R, Goyette G, Medjahed H, Perreault J, Tremblay T, Lewin A, Gokool L, Morrisseau C, Bégin P, Tremblay C, Martel-Laferrière V, Kaufmann DE, Richard J, Bazin R, Finzi A. Beaudoin-Bussières G, et al. Among authors: gasser r. mBio. 2020 Oct 16;11(5):e02590-20. doi: 10.1128/mBio.02590-20. mBio. 2020. PMID: 33067385 Free PMC article.
1,084 results