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Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation.
Fang C, Wang Z, Han C, Safgren SL, Helmin KA, Adelman ER, Serafin V, Basso G, Eagen KP, Gaspar-Maia A, Figueroa ME, Singer BD, Ratan A, Ntziachristos P, Zang C. Fang C, et al. Genome Biol. 2020 Sep 15;21(1):247. doi: 10.1186/s13059-020-02152-7. Genome Biol. 2020. PMID: 32933554 Free PMC article.
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.
Jin Q, Gutierrez Diaz B, Pieters T, Zhou Y, Narang S, Fijalkwoski I, Borin C, Van Laere J, Payton M, Cho BK, Han C, Sun L, Serafin V, Yacu G, Von Loocke W, Basso G, Veltri G, Dreveny I, Ben-Sahra I, Goo YA, Safgren SL, Tsai YC, Bornhauser B, Suraneni PK, Gaspar-Maia A, Kandela I, Van Vlierberghe P, Crispino JD, Tsirigos A, Ntziachristos P. Jin Q, et al. Among authors: gaspar maia a. Sci Adv. 2022 Dec 9;8(49):eabq8437. doi: 10.1126/sciadv.abq8437. Epub 2022 Dec 9. Sci Adv. 2022. PMID: 36490346 Free PMC article.
MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming.
Mohammed Ismail W, Mazzone A, Ghiraldini FG, Kaur J, Bains M, Munankarmy A, Bagwell MS, Safgren SL, Moore-Weiss J, Buciuc M, Shimp L, Leach KA, Duarte LF, Nagi CS, Carcamo S, Chung CY, Hasson D, Dadgar N, Zhong J, Lee JH, Couch FJ, Revzin A, Ordog T, Bernstein E, Gaspar-Maia A. Mohammed Ismail W, et al. Among authors: gaspar maia a. Commun Biol. 2023 Feb 23;6(1):215. doi: 10.1038/s42003-023-04571-1. Commun Biol. 2023. PMID: 36823213 Free PMC article.
Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia.
Binder M, Carr RM, Lasho TL, Finke CM, Mangaonkar AA, Pin CL, Berger KR, Mazzone A, Potluri S, Ordog T, Robertson KD, Marks DL, Fernandez-Zapico ME, Gaspar-Maia A, Patnaik MM. Binder M, et al. Among authors: gaspar maia a. Nat Commun. 2022 Mar 17;13(1):1434. doi: 10.1038/s41467-022-29142-6. Nat Commun. 2022. PMID: 35301312 Free PMC article.
Chd1 regulates open chromatin and pluripotency of embryonic stem cells.
Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M. Gaspar-Maia A, et al. Nature. 2009 Aug 13;460(7257):863-8. doi: 10.1038/nature08212. Epub 2009 Jul 8. Nature. 2009. PMID: 19587682 Free PMC article.
Stem cells and reprogramming: breaking the epigenetic barrier?
Ang YS, Gaspar-Maia A, Lemischka IR, Bernstein E. Ang YS, et al. Trends Pharmacol Sci. 2011 Jul;32(7):394-401. doi: 10.1016/j.tips.2011.03.002. Epub 2011 May 27. Trends Pharmacol Sci. 2011. PMID: 21621281 Free PMC article. Review.
MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation.
O'Loghlen A, Muñoz-Cabello AM, Gaspar-Maia A, Wu HA, Banito A, Kunowska N, Racek T, Pemberton HN, Beolchi P, Lavial F, Masui O, Vermeulen M, Carroll T, Graumann J, Heard E, Dillon N, Azuara V, Snijders AP, Peters G, Bernstein E, Gil J. O'Loghlen A, et al. Cell Stem Cell. 2012 Jan 6;10(1):33-46. doi: 10.1016/j.stem.2011.12.004. Cell Stem Cell. 2012. PMID: 22226354 Free PMC article.
24 results