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The New Antitumor Drug ABTL0812 Inhibits the Akt/mTORC1 Axis by Upregulating Tribbles-3 Pseudokinase.
Erazo T, Lorente M, López-Plana A, Muñoz-Guardiola P, Fernández-Nogueira P, García-Martínez JA, Bragado P, Fuster G, Salazar M, Espadaler J, Hernández-Losa J, Bayascas JR, Cortal M, Vidal L, Gascón P, Gómez-Ferreria M, Alfón J, Velasco G, Domènech C, Lizcano JM. Erazo T, et al. Among authors: gascon p. Clin Cancer Res. 2016 May 15;22(10):2508-19. doi: 10.1158/1078-0432.CCR-15-1808. Epub 2015 Dec 15. Clin Cancer Res. 2016. PMID: 26671995 Free article. Clinical Trial.
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer.
Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V. Garcia-Recio S, et al. Among authors: gascon p. Cancer Res. 2013 Nov 1;73(21):6424-34. doi: 10.1158/0008-5472.CAN-12-4573. Epub 2013 Sep 12. Cancer Res. 2013. PMID: 24030979 Free article.
Histamine receptor 1 inhibition enhances antitumor therapeutic responses through extracellular signal-regulated kinase (ERK) activation in breast cancer.
Fernández-Nogueira P, Noguera-Castells A, Fuster G, Recalde-Percaz L, Moragas N, López-Plana A, Enreig E, Jauregui P, Carbó N, Almendro V, Gascón P, Bragado P, Mancino M. Fernández-Nogueira P, et al. Among authors: gascon p. Cancer Lett. 2018 Jun 28;424:70-83. doi: 10.1016/j.canlet.2018.03.014. Epub 2018 Mar 14. Cancer Lett. 2018. PMID: 29548821 Free article.
Tumor promoting effects of CD95 signaling in chemoresistant cells.
Ametller E, García-Recio S, Costamagna D, Mayordomo C, Fernández-Nogueira P, Carbó N, Pastor-Arroyo EM, Gascón P, Almendro V. Ametller E, et al. Among authors: gascon p. Mol Cancer. 2010 Jun 23;9:161. doi: 10.1186/1476-4598-9-161. Mol Cancer. 2010. PMID: 20573240 Free PMC article.
Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis.
Zubeldia-Plazaola A, Recalde-Percaz L, Moragas N, Alcaraz M, Chen X, Mancino M, Fernández-Nogueira P, Prats de Puig M, Guzman F, Noguera-Castells A, López-Plana A, Enreig E, Carbó N, Almendro V, Gascón P, Bragado P, Fuster G. Zubeldia-Plazaola A, et al. Among authors: gascon p. Breast Cancer Res. 2018 Jul 4;20(1):65. doi: 10.1186/s13058-018-0977-z. Breast Cancer Res. 2018. PMID: 29973218 Free PMC article.
Comparison of methods for the isolation of human breast epithelial and myoepithelial cells.
Zubeldia-Plazaola A, Ametller E, Mancino M, Prats de Puig M, López-Plana A, Guzman F, Vinyals L, Pastor-Arroyo EM, Almendro V, Fuster G, Gascón P. Zubeldia-Plazaola A, et al. Among authors: gascon p. Front Cell Dev Biol. 2015 May 21;3:32. doi: 10.3389/fcell.2015.00032. eCollection 2015. Front Cell Dev Biol. 2015. PMID: 26052514 Free PMC article.
Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis.
Wu MZ, Chen SF, Nieh S, Benner C, Ger LP, Jan CI, Ma L, Chen CH, Hishida T, Chang HT, Lin YS, Montserrat N, Gascon P, Sancho-Martinez I, Izpisua Belmonte JC. Wu MZ, et al. Among authors: gascon p. Cancer Res. 2015 Sep 15;75(18):3912-24. doi: 10.1158/0008-5472.CAN-14-3208. Epub 2015 Aug 20. Cancer Res. 2015. PMID: 26294212 Free article.
315 results