SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
Sociali G, Grozio A, Caffa I, Schuster S, Becherini P, Damonte P, Sturla L, Fresia C, Passalacqua M, Mazzola F, Raffaelli N, Garten A, Kiess W, Cea M, Nencioni A, Bruzzone S.
Sociali G, et al. Among authors: garten a.
FASEB J. 2019 Mar;33(3):3704-3717. doi: 10.1096/fj.201800321R. Epub 2018 Dec 4.
FASEB J. 2019.
PMID: 30514106
Free PMC article.
BxPC-3 cells and MCF-7 cells were engineered to overexpress a catalytically active or a catalytically inactive SIRT6 form or were engineered to silence endogenous SIRT6 expression. ...The use of SIRT6 inhibitors, together with agents inducing oxidative stress, may r …
BxPC-3 cells and MCF-7 cells were engineered to overexpress a catalytically active or a catalytically inactive SIRT6 form or w …