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Functionally diverse type V CRISPR-Cas systems.
Yan WX, Hunnewell P, Alfonse LE, Carte JM, Keston-Smith E, Sothiselvam S, Garrity AJ, Chong S, Makarova KS, Koonin EV, Cheng DR, Scott DA. Yan WX, et al. Among authors: garrity aj. Science. 2019 Jan 4;363(6422):88-91. doi: 10.1126/science.aav7271. Epub 2018 Dec 6. Science. 2019. PMID: 30523077
Engineered Cas12i2 is a versatile high-efficiency platform for therapeutic genome editing.
McGaw C, Garrity AJ, Munoz GZ, Haswell JR, Sengupta S, Keston-Smith E, Hunnewell P, Ornstein A, Bose M, Wessells Q, Jakimo N, Yan P, Zhang H, Alfonse LE, Ziblat R, Carte JM, Lu WC, Cerchione D, Hilbert B, Sothiselvam S, Yan WX, Cheng DR, Scott DA, DiTommaso T, Chong S. McGaw C, et al. Among authors: garrity aj. Nat Commun. 2022 May 20;13(1):2833. doi: 10.1038/s41467-022-30465-7. Nat Commun. 2022. PMID: 35595757 Free PMC article.
Optical Pooled Screens in Human Cells.
Feldman D, Singh A, Schmid-Burgk JL, Carlson RJ, Mezger A, Garrity AJ, Zhang F, Blainey PC. Feldman D, et al. Among authors: garrity aj. Cell. 2019 Oct 17;179(3):787-799.e17. doi: 10.1016/j.cell.2019.09.016. Cell. 2019. PMID: 31626775 Free PMC article.
Genetic and transcriptional evolution alters cancer cell line drug response.
Ben-David U, Siranosian B, Ha G, Tang H, Oren Y, Hinohara K, Strathdee CA, Dempster J, Lyons NJ, Burns R, Nag A, Kugener G, Cimini B, Tsvetkov P, Maruvka YE, O'Rourke R, Garrity A, Tubelli AA, Bandopadhayay P, Tsherniak A, Vazquez F, Wong B, Birger C, Ghandi M, Thorner AR, Bittker JA, Meyerson M, Getz G, Beroukhim R, Golub TR. Ben-David U, et al. Nature. 2018 Aug;560(7718):325-330. doi: 10.1038/s41586-018-0409-3. Epub 2018 Aug 8. Nature. 2018. PMID: 30089904 Free PMC article.
CloneSifter: enrichment of rare clones from heterogeneous cell populations.
Feldman D, Tsai F, Garrity AJ, O'Rourke R, Brenan L, Ho P, Gonzalez E, Konermann S, Johannessen CM, Beroukhim R, Bandopadhayay P, Blainey PC. Feldman D, et al. Among authors: garrity aj. BMC Biol. 2020 Nov 24;18(1):177. doi: 10.1186/s12915-020-00911-3. BMC Biol. 2020. PMID: 33234154 Free PMC article.