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Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: garovic vd. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
Ureteral obstruction in cancer patients: a qualitative study.
Kumar A, Mynderse L, Patel K, Grudem M, Bakkum-Gamez J, Longenbach S, Block MS, Pitot HC, Garovic V, Weroha SJ, Jatoi A. Kumar A, et al. Psychooncology. 2016 May;25(5):605-9. doi: 10.1002/pon.3889. Epub 2015 Jun 22. Psychooncology. 2016. PMID: 26101949 No abstract available.
Targeting senescent cells alleviates obesity-induced metabolic dysfunction.
Palmer AK, Xu M, Zhu Y, Pirtskhalava T, Weivoda MM, Hachfeld CM, Prata LG, van Dijk TH, Verkade E, Casaclang-Verzosa G, Johnson KO, Cubro H, Doornebal EJ, Ogrodnik M, Jurk D, Jensen MD, Chini EN, Miller JD, Matveyenko A, Stout MB, Schafer MJ, White TA, Hickson LJ, Demaria M, Garovic V, Grande J, Arriaga EA, Kuipers F, von Zglinicki T, LeBrasseur NK, Campisi J, Tchkonia T, Kirkland JL. Palmer AK, et al. Aging Cell. 2019 Jun;18(3):e12950. doi: 10.1111/acel.12950. Epub 2019 Mar 25. Aging Cell. 2019. PMID: 30907060 Free PMC article.
Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia.
Suvakov S, Cubro H, White WM, Butler Tobah YS, Weissgerber TL, Jordan KL, Zhu XY, Woollard JR, Chebib FT, Milic NM, Grande JP, Xu M, Tchkonia T, Kirkland JL, Lerman LO, Garovic VD. Suvakov S, et al. Among authors: garovic vd. Biol Sex Differ. 2019 Sep 14;10(1):49. doi: 10.1186/s13293-019-0263-5. Biol Sex Differ. 2019. PMID: 31521202 Free PMC article.
Mechanisms of vascular dysfunction in the interleukin-10-deficient murine model of preeclampsia indicate nitric oxide dysregulation.
Cubro H, Nath KA, Suvakov S, Garcia-Valencia O, Parashuram S, White WM, Weissgerber TL, Nath MC, Milic NM, Sontag F, d'Uscio LV, Zhu Y, Kirkland JL, Tchkonia T, Alexander MP, Quinton RA, Katusic ZS, Grande JP, Garovic VD. Cubro H, et al. Among authors: garovic vd. Kidney Int. 2021 Mar;99(3):646-656. doi: 10.1016/j.kint.2020.09.034. Epub 2020 Nov 2. Kidney Int. 2021. PMID: 33144212 Free PMC article.
Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies.
Suvakov S, Ghamrawi R, Cubro H, Tu H, White WM, Tobah YSB, Milic NM, Grande JP, Cunningham JM, Chebib FT, Prata LGPL, Zhu Y, Tchkonia T, Kirkland JL, Nath KA, Milosavljevic A, Garovic VD. Suvakov S, et al. Among authors: garovic vd. EBioMedicine. 2021 Aug;70:103536. doi: 10.1016/j.ebiom.2021.103536. Epub 2021 Aug 11. EBioMedicine. 2021. PMID: 34391091 Free PMC article.
217 results